Tag: Tenofovir side effects

While tenofovir is a highly effective antiviral drug, its different formulations have distinct safety profiles. A key question for patients and clinicians is which of the following side effects is common with tenofovir, particularly when comparing the older tenofovir disoproxil fumarate (TDF) and the newer tenofovir alafenamide (TAF). The answer depends heavily on the specific formulation and individual patient factors.

Over 10,000 HIV-positive individuals on tenofovir disoproxil fumarate (TDF) showed an increased risk for chronic kidney disease. This highlights that a major side effect of tenofovir, particularly the older TDF formulation, is renal and bone toxicity, which necessitates careful monitoring and management by healthcare professionals.