Tag: Tensilon test

In 2021, the prevalence of myasthenia gravis (MG) in the United States was estimated to be 37.0 per 100,000 people [1.6.1]. For those managing this condition, understanding medication interactions is crucial. So, can you use atropine in myasthenia gravis? The answer is complex and highly situational.

Though once a vital diagnostic tool for myasthenia gravis, the FDA discontinued edrophonium in the U.S. for this purpose in 2018, citing a high rate of false-positive results. The function of edrophonium, however, stems from its mechanism as a short-acting acetylcholinesterase inhibitor.

In 2018, the U.S. Food and Drug Administration (FDA) discontinued the use of edrophonium, effectively ending the era of the Tensilon test as a diagnostic tool for myasthenia gravis. This decision was driven by the test's inherent limitations and the advent of safer, more accurate diagnostic methods.