What is the antidote for extravasation of both norepinephrine and dopamine?
•
5 min read
Over 97% of reported vasopressor extravasation events that resulted in local tissue injury were from peripheral intravenous administration. For extravasation of norepinephrine and dopamine, the primary antidote is phentolamine, an alpha-adrenergic blocker that reverses the intense vasoconstriction causing tissue damage.