Tag: Tetracyclic

Marketed under the brand name Ludiomil, maprotiline was one of the first tetracyclic antidepressants to be developed and used to treat depression and anxiety. This medication primarily works by increasing the levels of norepinephrine in the brain, but it is no longer widely available in the U.S. due to its side effect profile and the development of newer treatments.

Originally approved by the U.S. Food and Drug Administration (FDA) in the late 1970s for the treatment of depression, amoxapine is a long-standing medication with a complex profile. This article clarifies what is the classification of amoxapine, examining its structural and pharmacological distinctions that set it apart from other antidepressants.