Tag: Tham

The brand-name medication *Tham* (tromethamine) was discontinued by its sole manufacturer in 2016, leading to a prolonged drug shortage. However, after a determination by the FDA that the withdrawal was not due to safety or effectiveness concerns, generic versions of tromethamine have since been approved and successfully launched, making the medication available to patients again.

Tromethamine is a systemic alkalizing agent that acts as a proton acceptor to help treat or prevent acid problems in the blood, a condition known as metabolic acidosis. This critical care medication serves a distinct purpose, separate from other well-known drugs that may use 'tromethamine' in their name as a salt form.

Tromethamine, commonly known as THAM, is a parenteral systemic alkalizing agent historically used for the prevention and correction of severe metabolic acidosis in critical care settings. It has specific applications, particularly during cardiac bypass surgery and cardiac arrest, where it helps sustain vital functions by neutralizing excess acid.

Tham, the brand name for tromethamine, is a systemic alkalizing agent that buffers excess acid in the body without producing carbon dioxide. Although it was temporarily discontinued by its manufacturer in 2016, generic versions of tromethamine are now available for critical care applications.