Tag: Thiopental

Propofol is the most widely used intravenous anesthetic due to its rapid onset and favorable recovery profile. But what type of medication is used to induce anesthesia besides this common agent, and how do their distinct mechanisms of action make them suitable for various patient needs and surgical situations?.

Developed in the 1930s, thiopental is a rapid-onset, short-acting barbiturate that became a cornerstone of anesthesia for decades [1.2.1, 1.9.3]. So, what is thiopental commonly used for? Its primary applications have been in inducing anesthesia, managing seizures, and protecting the brain during surgery [1.2.1, 1.2.4].

In 2011, Hospira Inc., the sole U.S. manufacturer, announced it would permanently cease production of thiopental [1.4.2]. The answer to **why is thiopental no longer used** involves a complex interplay of superior clinical alternatives, manufacturing challenges, and ethical controversies tied to its use in capital punishment.

Despite being largely replaced by newer agents in many countries, thiopental, a potent barbiturate, is still used in some clinical settings. Understanding what are the side effects of thiopental is crucial for both healthcare professionals and for its historical context in pharmacology.

Barbiturates were once widely prescribed as sedatives and hypnotics but have largely been replaced by newer drugs with wider therapeutic margins, such as benzodiazepines. However, specific barbiturate classes, including the ultra-short-acting varieties, continue to play specialized roles in modern medicine. Understanding **which of the following barbiturates is the shortest acting** is crucial for comprehending their unique pharmacological profiles and clinical applications.