Understanding the Limits of Therapy: Why no tPA after 3 hours?
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3 min read
According to the National Institute of Neurological Disorders and Stroke (NINDS) trial, patients treated with tPA within three hours of stroke onset were 30% more likely to experience minimal or no disability. This established the crucial time-sensitive nature of stroke treatment and is a core reason for the strict guidelines surrounding the question, “Why no tPA after 3 hours?”