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Tag: Tiva

Explore our medication guides and pharmacology articles within this category.

What is the 10/8-6 rule for propofol? An Overview of a Manual Infusion Regimen

4 min read
First developed in the 1990s through computer simulations, the **what is the 10/8-6 rule for propofol?** describes a simplified manual infusion scheme for continuous propofol administration. This step-down dosing approach was designed to help clinicians maintain a stable, targeted blood concentration of the anesthetic drug during total intravenous anesthesia (TIVA).

What is the 10 8 6 rule for propofol?

4 min read
Originally derived from pharmacokinetic simulations in the late 1980s, the **10 8 6 rule for propofol** is a manual infusion regimen designed to help achieve and maintain a stable blood concentration during general anesthesia. This technique, also known as the Roberts or Bristol regimen, provides a foundational understanding of propofol's redistribution in the body, although it has largely been supplemented by modern computer-controlled methods.