Tag: Tocolytic

Preterm birth, occurring before 37 weeks of gestation, is a primary cause of perinatal morbidity and mortality globally [1.2.1]. An important pharmacological intervention involves asking, **what is an example of an oxytocin receptor antagonist?** The most prominent clinical example is atosiban, a drug designed to halt uterine contractions [1.2.4].

Did you know that nifedipine was first reported for use in tocolysis—the inhibition of uterine contractions—in 1980? This calcium channel blocker is now a first-line therapy for suppressing preterm labor by relaxing the uterine muscles, a key function that helps prolong pregnancy.

Preterm birth is a leading cause of neonatal morbidity and mortality worldwide. To combat this, medications called tocolytics are used to temporarily inhibit uterine contractions, with nifedipine being a common choice. The primary mechanism for how does nifedipine act as a tocolytic involves blocking the calcium channels necessary for muscle contraction.

Hypertensive disorders of pregnancy have been on the rise, with rates increasing from 13.3% to 15.9% between 2017 and 2019 [1.7.5]. This article explains why is nifedipine given to a pregnant woman to manage some of these critical conditions.

According to the American College of Obstetricians and Gynecologists (ACOG), extended-release nifedipine is considered a first-line medication for treating chronic hypertension in pregnancy, directly contradicting the idea that nifedipine is no longer used. The misconception stems from past issues with immediate-release formulations and earlier safety concerns, rather than a universal ban.

Magnesium is the second most plentiful cation within intracellular fluids and is essential for over 350 enzyme systems in the human body [1.2.1, 1.2.5]. This article explains what is magnesium sulphate in pharmacy, detailing its critical roles from seizure prevention to electrolyte replacement.