Tag: Topoisomerase inhibitor

Derived from the 'Happy Tree' (*Camptotheca acuminata*), 10-hydroxycamptothecin (HCPT) is a potent topoisomerase I inhibitor [1.2.1, 1.2.2]. So, **what is 10-hydroxycamptothecin used for?** It forms the backbone of crucial anticancer therapies, particularly for colorectal, ovarian, and lung cancers [1.3.1, 1.3.3].

Camptosar is a key chemotherapy agent used in the treatment of metastatic colorectal cancer, a disease that affects thousands of individuals annually [1.4.2, 1.4.3]. So, what type of drug is Camptosar? It is classified as a topoisomerase I inhibitor, a type of antineoplastic (cancer) medicine [1.2.1, 1.2.7].