Tag: Toxic optic neuropathy

While less frequent than peripheral neuropathy, isoniazid is a documented cause of optic neuritis, often linked to its interference with vitamin B6 metabolism. This potentially reversible neurological side effect underscores the importance of patient monitoring and preventative measures during tuberculosis treatment.

While ethambutol is the most commonly implicated antitubercular drug for causing optic neuritis, the question remains: **Does rifampin cause optic neuritis?** This article examines the evidence regarding rifampin's potential for ocular toxicity.

Ethambutol-induced optic neuropathy (EON) occurs in a small percentage, estimated at 1–2%, of patients receiving the antitubercular agent ethambutol, causing significant, and sometimes permanent, vision loss. The condition, characterized as retrobulbar optic neuritis, is one of the most serious side effects associated with this medication.

Affecting up to 2% of patients treated with the anti-tuberculosis drug ethambutol, optic neuropathy (EON) is a serious and potentially irreversible side effect. It is a toxic optic neuropathy where the drug's damaging effects on the optic nerve cause inflammation and vision loss. Understanding **how does ethambutol cause optic neuritis** is crucial for early detection and preventing permanent visual impairment.