Tag: Transplant drugs

While tacrolimus has revolutionized organ transplant outcomes, it is not always effective, with some patients experiencing acute rejection despite therapy. In cases of tacrolimus rejection, clinicians must turn to a range of alternative or supplementary medications to stabilize the allograft and prevent irreversible damage. This comprehensive guide explores the pharmacology and management strategies for dealing with rejection when a patient is already on tacrolimus.

Initially discovered in soil from Easter Island (Rapa Nui) in the 1970s, the drug rapamycin is typically used as a powerful immunosuppressant to prevent organ rejection in transplant patients. However, groundbreaking research in model organisms has raised the fascinating question: **What transplant drug slows aging?**