Exploring Why is Atropine Contraindicated in Down Syndrome: A Pharmacological Analysis
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5 min read
Historically, concerns have been raised regarding the use of atropine in individuals with Down syndrome (Trisomy 21), driven by reports of increased susceptibility to toxic effects. This has led to a traditional caution and, in many cases, a firm belief that atropine is contraindicated in Down syndrome patients due to their unique physiological profile, particularly concerning the autonomic nervous system.
