Tag: Tropical disease

Leishmaniasis is a tropical disease affecting hundreds of thousands of people annually worldwide, causing a wide range of clinical presentations. The drug Glucantime (meglumine antimoniate), a pentavalent antimonial, has been a cornerstone in treating this parasitic infection for decades.

Leishmaniasis affects millions worldwide, with approximately 700,000 to 1 million new cases annually. A primary historical and current treatment for this disease is sodium stibogluconate, which is a key component in the fight against this debilitating parasitic infection.

An estimated 6 to 7 million people worldwide are infected with Chagas disease, a potentially life-threatening illness caused by the parasite *Trypanosoma cruzi*. The drug **nifurtimox** is a critical antiprotozoal medication used in the treatment of this disease, with specific indications for pediatric patients.

Globally, more than 200 million people are infected with parasitic flatworms that cause the disease schistosomiasis. Oxamniquine is a medication that was developed to combat this disease and is specifically used to treat infections caused by *Schistosoma mansoni*. Though it has largely been replaced by praziquantel as the first-line treatment, it remains a critical second-line agent, especially in cases where praziquantel is not effective or cannot be tolerated.