Tag: Trough level

Tacrolimus has a narrow therapeutic range, which means the blood level needs to be carefully maintained to be effective without causing toxicity. This is why there is no single answer to what is a normal tacrolimus level; the target is highly individualized based on the organ transplant and time since surgery.

Pharmacology research has shown that the trough levels are often the most reliable measurement for monitoring drug elimination and preventing toxicity. To achieve safe and effective treatment, healthcare providers must understand what is ctrough, the lowest concentration of a medication in the bloodstream before the next dose is administered.

The global therapeutic drug monitoring market was valued at USD 1.80 billion in 2023, highlighting the importance of precise dosing [1.9.1]. A key component of this is understanding **what is a drug trough**, the lowest concentration of a medication in the body before the next dose.