Tag: Tryptamines

Structurally, N,N-dimethyltryptamine (DMT) is very similar to the naturally occurring neurotransmitter serotonin. Both are classified as tryptamines and share an indole and an ethylamine group, yet they produce vastly different effects on the brain due to slight molecular differences. Understanding how DMT is similar to serotonin is key to grasping how this powerful psychedelic compound exerts its influence.

Surveys show that as of 2021, approximately 9% of people who have used recreational drugs have tried DMT [1.7.1]. But for those unfamiliar, **what does DMT compare to?** This powerful psychedelic is often mentioned alongside substances like psilocybin and LSD, but it possesses a unique profile.

With potency estimated at 4 to 20 times that of regular DMT, 5-methoxy-N,N-dimethyltryptamine ($5-MeO-DMT$) is widely regarded as what is the most powerful DMT in terms of psychedelic intensity. This naturally occurring and synthetically produced tryptamine has a distinctive pharmacological profile and profound, though brief, effects on consciousness.