Tag: Tubocurarine

First isolated in 1897, d-tubocurarine is a benzylisoquinoline alkaloid derived from curare, which famously causes paralysis by blocking signals at the neuromuscular junction. This article explores *how does tubocurarine cause paralysis* by delving into its specific competitive antagonistic action on skeletal muscle receptors.

Curine is the principal bisbenzylisoquinoline alkaloid (BBA) obtained from the plant *Chondrodendron platyphyllum* [1.2.1], a key ingredient in the historic South American arrow poison known as curare [1.3.4, 1.7.2]. So, what does curine do? Its primary role is as a potent muscle relaxant.