Does medroxyprogesterone cause tumors? A detailed look at the evidence
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5 min read
Recent studies, including research published in 2024 and 2025, have found that long-term use of injectable medroxyprogesterone acetate (MPA), commonly known as Depo-Provera, is associated with a significantly increased risk of meningiomas, a type of brain tumor. This raises a critical question for many users and healthcare providers: **Does medroxyprogesterone cause tumors?** While the evidence for meningiomas is growing, the relationship between medroxyprogesterone and other tumor types, including breast cancer, is more complex and depends heavily on the context of its use.
