Tag: Ubrogepant

According to prescribing information, Ubrelvy (ubrogepant) is contraindicated with certain strong CYP3A4 inhibitors, such as ketoconazole, due to a significant risk of increased drug exposure and adverse effects. This guide explains exactly what not to mix with Ubrelvy, covering potential dangers from specific medications, supplements, and foods, to ensure patient safety.

Recent studies have found that the combination of a daily preventive migraine treatment like Qulipta with an as-needed acute treatment like Ubrelvy can be safe and well-tolerated for many patients [1.4.1]. So, can I take Ubrelvy if I take Qulipta? It's a question many migraine sufferers are asking.

According to the American Migraine Foundation, migraine is the third most prevalent illness in the world, affecting more than a billion people globally. While both Qulipta (atogepant) and UBRELVY (ubrogepant) target the same migraine-related protein, they do not work the same because one is used for prevention while the other is used for acute treatment.

Migraine affects approximately 15% of the global population, but recent breakthroughs in the biotech industry have led to novel treatments targeting a specific neuropeptide. The new 'Wonder drug' for migraines is not a single pill, but an entire class of drugs known as gepants, which are specifically designed to disrupt the migraine pathway.

Millions of people worldwide suffer from debilitating migraines, and the development of CGRP-targeting medications has provided new relief. However, patients often wonder: **Are QULIPTA and Ubrelvy the same**? While both belong to the same class of drugs, they are used for fundamentally different purposes in migraine management.

Butalbital, a barbiturate, can significantly reduce the blood levels and effectiveness of the CGRP inhibitor Ubrelvy. This major drug interaction is caused by butalbital inducing the CYP3A4 enzyme, which metabolizes Ubrelvy more quickly. A medical professional's guidance is essential to determine if you can take Ubrelvy with butalbital.