Tag: Ultrafiltration

Nearly 1 in 5 intensive care unit patients with acute kidney injury require some form of renal replacement therapy, which often involves ultrafiltration and can significantly impact antibiotic concentrations. The question of whether ultrafiltration removes antibiotics is complex, with the answer depending heavily on the specific drug and filtration conditions.

Vancomycin, a critical antibiotic for treating serious Gram-positive infections, has complex pharmacokinetics, especially in patients with impaired renal function. Studies show its serum levels are significantly reduced during certain types of ultrafiltration and renal replacement therapy, making the question, **'Is vancomycin removed during ultrafiltration?'** highly relevant for managing patient dosing and treatment efficacy.

Vancomycin clearance is significantly affected by the type of dialysis, with high-flux membranes removing a substantial amount of the drug, unlike older, low-flux filters. This has major implications for proper dosing and underscores why clinicians and patients must understand if and how **ultrafiltration dialysis remove vancomycin**.