Tag: Vigabatrin

According to the Medicines and Healthcare products Regulatory Agency (MHRA) guidance, anti-seizure medications (ASMs) are classified into three categories based on the risk associated with switching between different manufacturers' products. This classification is crucial for prescribing protocols, especially when considering generic versions, and provides clear guidance on **what are the Category 3 anti epileptics**, a group considered to have an extremely low risk for brand interchange.

Depression has been linked to lower levels of GABA in the brain [1.6.1]. GABA inhibitors are a diverse group of substances that interfere with the primary inhibitory neurotransmitter in the central nervous system. So, what drugs are GABA inhibitors? They work through various mechanisms, including blocking receptors or preventing GABA's breakdown or reuptake.

In controlled clinical trials, up to 40% of adults taking the antiepileptic drug vigabatrin reported experiencing fatigue, a side effect that can significantly impact daily life. This drowsiness and tiredness, also known as somnolence, is a well-documented side effect of the medication.

While the vast majority of medications are safe for ophthalmic health, a small number of therapeutic and illicit drugs are known to cause irreversible damage to the eyes. Understanding **what drugs cause permanent blindness** is critical for patients, prescribers, and eye care professionals to prevent severe vision loss.

According to the Ethiopian Food and Drug Administration (EFDA), **Vigafen** is a brand name for the non-steroidal anti-inflammatory drug (NSAID) ketoprofen lysine salt, used to treat pain and inflammation. Due to its name, it is often confused with vigabatrin, a potent anti-epileptic medication associated with a serious risk of permanent vision loss.