Which is more effective, sitagliptin or vildagliptin? A comprehensive comparison
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5 min read
As two of the most widely used dipeptidyl peptidase-4 (DPP-4) inhibitors for type 2 diabetes, sitagliptin (Januvia) and vildagliptin (Galvus) both work by increasing levels of incretin hormones to help lower blood glucose. While both are effective, patients and clinicians often ask: which is more effective, sitagliptin or vildagliptin? A closer look at their pharmacological profiles and clinical trial data reveals some important differences, particularly concerning glucose fluctuations and dosing frequency.