Tag: Vioxx

According to a resource compiling drug withdrawal data, more than 578 drugs have been withdrawn or discontinued from markets globally due to various reasons, with safety issues being a primary cause. This highlights the critical nature of understanding what medications have been discontinued and why.

Between 1953 and 2013, 462 medications were withdrawn worldwide, primarily due to adverse reactions [1.9.4]. Understanding what drugs are discontinued involves looking at safety, efficacy, and commercial factors that lead to their removal from the market.

Contrary to a widely-held belief, Celebrex (celecoxib) was *not* taken off the market; rather, its counterparts Vioxx and Bextra were. The question, **Why did Celebrex get taken off the market?**, stems from a widespread safety controversy involving the entire class of COX-2 inhibitor drugs in the early 2000s.

From 2013 to 2018, nearly 8,000 medications were recalled by pharmaceutical companies [1.8.5]. Several of these have been prominent painkillers. So, what pain medication was removed from the market, and for what reasons? This reveals much about post-market drug safety.

An estimated 30 million people use nonsteroidal anti-inflammatory drugs (NSAIDs) every day worldwide [1.11.1]. While generally effective, some have been taken off the market. This article explores which NSAIDs are banned and the reasons for their withdrawal.

In 2004, Merck's voluntary withdrawal of Vioxx, a popular pain reliever, impacted an estimated 20 million Americans who had taken the drug [1.9.2]. The central question became, **what NSAID was taken off the market** and for what reasons? This event triggered a major re-evaluation of drug safety.

In one of the largest voluntary drug recalls in history, Merck & Co. withdrew its blockbuster arthritis drug Vioxx (rofecoxib) from the worldwide market on September 30, 2004. The recall followed concerns and clinical trial data indicating Vioxx increased the risk of heart attack and stroke.

In 2007, an FDA advisory committee voted 20 to 1 against approving etoricoxib (Arcoxia), determining that its cardiovascular risks did not justify its therapeutic benefits. This rejection effectively banned the COX-2 inhibitor from the US market, a significant event in the wake of similar safety controversies.

In 2004, the pharmaceutical company Merck voluntarily withdrew the blockbuster arthritis drug Vioxx from the worldwide market after new study data revealed an increased risk of heart attacks and strokes. Because of this recall, it is not possible to buy Vioxx anymore and has not been available for purchase for over two decades.

Between 1953 and 2013, 462 medicinal products were withdrawn from the market due to adverse reactions [1.7.1]. When wondering, 'What pain pill did they take off the market?', several prominent examples come to mind, including propoxyphene (Darvocet) and rofecoxib (Vioxx) [1.2.2, 1.2.1].