What is the mechanism of action of enfuvirtide? An HIV Fusion Inhibitor Explained
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4 min read
Approved by the FDA in 2003, enfuvirtide (Fuzeon) was the first HIV fusion inhibitor to be introduced, representing a new class of antiretroviral drugs. The mechanism of action of enfuvirtide involves a unique, extracellular approach to inhibit the fusion of the human immunodeficiency virus (HIV) with healthy host cells, thereby preventing viral replication.