How Do Opioids Inhibit GABA? A Neurobiological Perspective
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4 min read
Chronic pain affects about 30% of the population worldwide, and opioids are a primary treatment [1.6.8]. Central to their powerful effects is a critical question: How do opioids inhibit GABA, the brain's main inhibitory neurotransmitter, to produce their well-known analgesic and euphoric effects? [1.6.8]