Tag: Wearing off

Over 81% of patients with Parkinson's disease are treated with anti-Parkinson drugs, with levodopa being the most common [1.8.2]. Learning how to reduce side effects of carbidopa-levodopa is key to improving quality of life and treatment efficacy.

According to a 2021 study, more than 60% of people with multiple sclerosis (MS) using ocrelizumab (Ocrevus) experience a "wearing-off" phenomenon, where symptoms increase before the next scheduled infusion. This common occurrence often leads patients to question: does Ocrevus stop working?

In the United States, nearly 90,000 people are diagnosed with Parkinson's disease each year [1.10]. For many, a key question becomes **what is Comtan prescribed for?** This medication serves as an adjunctive therapy to manage symptoms as the disease progresses.

Patients with Parkinson's disease (PD) who have been on long-term levodopa therapy often face motor fluctuations and disabling "off" episodes as the medication's effect wears off. For these individuals, understanding what are the benefits of taking opicapone becomes crucial for optimizing treatment and improving their quality of life. Opicapone is a third-generation catechol-O-methyltransferase (COMT) inhibitor, which plays a key role in extending the availability of levodopa in the brain.