How does desmopressin increase von Willebrand factor?
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3 min read
According to the National Institutes of Health, desmopressin (DDAVP) is a synthetic hormone analog used to manage various bleeding disorders. It works by significantly increasing the plasma levels of von Willebrand factor (VWF), a key protein essential for normal blood clotting. This rapid increase is achieved through a specific cellular mechanism, rather than by stimulating the creation of new VWF.