What Enzymes Metabolize SSRI? A Pharmacological Overview
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4 min read
The majority of prescribed Selective Serotonin Reuptake Inhibitors (SSRIs) are metabolized by the Cytochrome P450 (CYP) enzyme system, primarily in the liver. Understanding which enzymes metabolize SSRI drugs is crucial for predicting potential drug-drug interactions and explaining individual variations in treatment response and side effects. These metabolic pathways are influenced by genetic factors, a field known as pharmacogenetics.
