What medication most commonly causes osteonecrosis? A look at bisphosphonates and corticosteroids
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5 min read
According to estimates, corticosteroid-induced osteonecrosis alone accounts for over 10% of the half-million total joint replacements performed annually in the U.S. Determining what medication most commonly causes osteonecrosis is complex, as it depends on the specific drug class and the affected part of the skeleton, with bisphosphonates and corticosteroids being the two primary culprits.