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The Meaning Behind the Name: What does A535 stand for?

4 min read

First introduced in Canada in 1919 under the name Antiphlogistine, the topical analgesic known as RUB A535 has been a staple for pain relief for over a century. Despite its popularity, the question of what does A535 stand for is a common point of confusion, with many people assuming the alphanumeric code is an acronym or a chemical formula.

Quick Summary

The alphanumeric code 'A535' is simply a product identifier chosen by the manufacturer for the popular Canadian topical analgesic, RUB A535. It is not an acronym for specific words. The cream uses counterirritant ingredients like methyl salicylate and menthol to provide temporary relief for muscle and joint aches.

Key Points

  • Not an Acronym: The 'A535' in RUB A535 is a brand identifier, not an abbreviation or acronym for specific words, chosen by the manufacturer, Church & Dwight.

  • Counterirritant Mechanism: RUB A535 is a topical analgesic that works by causing a distracting, mild irritation (cooling then warming) on the skin to help mask deeper muscle and joint pain.

  • Key Ingredients: Its active ingredients typically include methyl salicylate, menthol, camphor, and eucalyptus oil, which are responsible for its distinct cooling and warming sensations.

  • Canadian Origin: The product was originally introduced in Canada in 1919 under the name Antiphlogistine and was later rebranded as RUB A535.

  • Versus NSAIDs: Unlike NSAID creams (e.g., Voltaren) that reduce inflammation, RUB A535's primary action is to mask pain rather than treat its underlying cause.

  • Salicylate-based: Due to its methyl salicylate content, it is important to be cautious if you have a salicylate allergy, are taking blood thinners, or are pregnant.

In This Article

Demystifying the Name: The True Meaning of A535

Contrary to popular belief, the 'A535' in RUB A535 is not an acronym that stands for specific words or a detailed chemical name. Instead, it is a proprietary product identifier designated by the manufacturer, Church & Dwight. Similar to how many commercial products receive a unique alphanumeric code, the name serves to differentiate it in the marketplace. The product, originally a poultice named Antiphlogistine, was developed in Montreal, Quebec, Canada, and later rebranded as the cream we know today. This history confirms that the name is a matter of branding, not a pharmacological term or an abbreviation.

The Pharmacology of a Counterirritant

RUB A535's effectiveness is not based on a chemical name, but rather on the pharmacological action of its ingredients. The product is a topical analgesic, specifically operating as a counterirritant. This means it works by applying a mild irritation or sensation (in this case, cooling followed by warming) to the skin's surface to distract the nervous system from deeper, more intense muscle or joint pain. The sensation overrides the underlying pain signals, providing temporary relief. This is a different mechanism from nonsteroidal anti-inflammatory drugs (NSAIDs), which work by inhibiting inflammation at its source.

Key Active Ingredients in RUB A535

While the name A535 holds no specific meaning, the ingredients within the cream are what provide its therapeutic effects. Common formulations of the product typically include a combination of these active components:

  • Methyl Salicylate: A salicylate-based compound with analgesic properties, similar to aspirin. It contributes to the warming sensation on the skin, and its absorption may provide localized pain relief.
  • Menthol: Provides an initial cooling effect on the skin by stimulating the nerves responsible for cold perception.
  • Camphor: Also a counterirritant, it enhances the feeling of warmth when applied to the skin, helping to mask pain.
  • Eucalyptus Oil: Contributes to the distinctive scent and provides an additional counterirritant effect.

Formulations and Uses

Over the years, the RUB A535 product line has expanded beyond the original cream to include various options tailored for different pain types and consumer preferences. These products are used for temporary relief of minor aches and pains associated with:

  • Muscle strains and sprains
  • Arthritic pain and rheumatic pain
  • Backaches and lumbago
  • Stiff joints

Different strengths and formulas, including Extra Strength and odorless options, offer variations in the intensity of the counterirritant effect. Some formulas also contain other ingredients like Arnica, a traditional herbal medicine used for inflammation, bumps, and bruises.

A535 vs. Other Topical Pain Relievers

Choosing the right topical pain reliever can depend on the specific type and severity of pain. Here is a comparison of RUB A535 with other common options:

Feature RUB A535 (Counterirritant) Voltaren (Topical NSAID) Lidocaine (Topical Anesthetic)
Mechanism of Action Creates cooling/warming sensation to distract from pain. Reduces inflammation by targeting prostaglandins. Numbes local nerve endings to block pain signals.
Active Ingredients Methyl Salicylate, Menthol, Camphor. Diclofenac Sodium 1%. Lidocaine.
Best For Minor muscle aches and joint pain. Inflammation-related pain (arthritis, sprains, tendonitis). Localized nerve or joint pain requiring a numbing effect.
Potential Side Effects Skin irritation, burning sensation, allergic reaction. Skin irritation, potential systemic absorption risks. Skin irritation, numbness, allergic reaction.
Precautions Avoid use if allergic to salicylates; use caution with anticoagulants. Consult doctor if using other NSAIDs; avoid during later pregnancy. Avoid on large skin areas or for prolonged use.

Important Safety Considerations

Before using any topical analgesic, including RUB A535, it is crucial to consider safety precautions. Some key warnings include:

  • Do not apply to damaged skin or wounds.
  • Avoid contact with eyes and mucous membranes.
  • Discontinue use if pain persists for more than seven days or if a rash or burning sensation occurs.
  • Consult a healthcare professional before use if you are pregnant, breastfeeding, or taking anticoagulant medications.
  • Never use heating pads on the treated area, as this can increase the risk of skin burns.
  • Children under 18 should not use salicylate-containing products if they have chickenpox or flu, due to the risk of Reye's syndrome.

Conclusion

In summary, the question of what does A535 stand for has a straightforward answer: it's a brand identifier, not an acronym. The pain-relieving power of RUB A535 comes from its active counterirritant ingredients—methyl salicylate, menthol, camphor, and eucalyptus oil—which create a cooling and warming sensation to mask muscle and joint pain. As a popular over-the-counter medication with a long history, it remains a trusted option for many Canadians seeking relief from minor aches, though it operates on a different pharmacological principle than NSAID-based creams like Voltaren. Understanding its mechanism and active ingredients is more important than knowing what its alphanumeric code means for effective and safe use.

Rub A535 official website

Frequently Asked Questions

No, the alphanumeric code 'A535' is simply a product identifier chosen by the manufacturer, Church & Dwight. It is not an acronym for a specific phrase or words.

The product was originally sold as a poultice called Antiphlogistine in Canada, starting in 1919. It was later developed into a topical analgesic cream and renamed RUB A535 in 1957.

RUB A535 functions as a counterirritant. The active ingredients create a cool-then-warm sensation on the skin, distracting the nerves from the deeper muscle or joint pain and providing temporary relief.

Common active ingredients include methyl salicylate, menthol, camphor, and eucalyptus oil. The exact concentration can vary depending on the specific product formulation.

Unlike anti-inflammatory NSAID creams like Voltaren, RUB A535 is a counterirritant. Its main function is to mask pain signals, not to reduce inflammation at its source.

Possible side effects include skin irritation, redness, or a burning sensation. In rare cases, more serious allergic reactions can occur. It's crucial to follow application instructions and avoid using heating pads on the area.

You should avoid using RUB A535 if you are allergic to salicylates, taking anticoagulant medications, or have a severe allergic reaction. It should not be used on open wounds or damaged skin.

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.