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The Risks and Realities: Can You Use Cortisone Cream Long Term?

5 min read

A 2022 survey found that adult eczema patients reported using topical corticosteroids for an average of 15.3 years [1.10.1]. This raises a critical question for many: can you use cortisone cream long term without significant risk? While effective for short-term relief, prolonged use is not recommended and carries potential side effects [1.2.1].

Quick Summary

Long-term use of cortisone cream is generally not advised due to risks like skin thinning, stretch marks, and topical steroid withdrawal [1.2.1, 1.2.2]. This overview details the proper use, potential dangers, and safer alternatives for managing chronic skin conditions.

Key Points

  • Short-Term Solution: Cortisone creams are intended for short-term use, typically 1-2 weeks for over-the-counter products, to control inflammation and itching [1.5.2, 1.7.2].

  • Risk of Skin Atrophy: The most common side effect of long-term use is skin thinning (atrophy), which makes the skin fragile and prone to damage [1.2.2, 1.4.2].

  • Topical Steroid Withdrawal (TSW): Prolonged use can lead to TSW, a condition where stopping the cream causes severe redness, burning, and peeling that can be worse than the original rash [1.4.3, 1.4.4].

  • Potency Matters: Risks increase significantly with higher potency (prescription-strength) steroids. Mild, over-the-counter hydrocortisone has a lower risk profile [1.2.4, 1.3.4].

  • Systemic Side Effects are Possible: Though rare, absorption of potent steroids into the bloodstream can cause systemic issues like HPA axis suppression, Cushing's syndrome, and glaucoma [1.2.3, 1.2.5].

  • Avoid Sensitive Skin: Use on thin-skinned areas like the face, groin, or underarms should only be done under strict medical supervision due to higher absorption and risk [1.7.1, 1.8.1].

  • Safer Alternatives Exist: For chronic management, non-steroidal options like calcineurin inhibitors, PDE4 inhibitors, and diligent moisturizing are recommended to avoid long-term steroid risks [1.6.2, 1.10.2].

In This Article

What Are Cortisone Creams (Topical Corticosteroids)?

Cortisone creams, more accurately known as topical corticosteroids (TCS), are anti-inflammatory medications applied to the skin [1.8.2]. They work by suppressing the local immune response to reduce inflammation, itching, and redness caused by various skin conditions [1.8.2]. These creams are a cornerstone treatment for inflammatory dermatoses like eczema and psoriasis [1.4.4, 1.10.2].

Topical steroids come in a wide range of potencies, from mild (Class 7), like over-the-counter hydrocortisone 1%, to superpotent (Class 1), such as clobetasol propionate, which is available only by prescription [1.3.1, 1.3.4]. The strength of the cream prescribed by a doctor depends on the severity of the skin condition, the location on the body, and the patient's age [1.9.2].

The Intended Use: Short-Term Relief

Cortisone creams are highly effective for providing rapid relief from flare-ups of inflammatory skin conditions. They are commonly prescribed for issues such as [1.4.4]:

  • Eczema (Atopic Dermatitis): To control itching and rashes.
  • Psoriasis: To reduce scaling and inflammation.
  • Contact Dermatitis: Resulting from allergic reactions to substances like soap or nickel.
  • Insect Bites and Stings: To lessen localized itching and swelling [1.5.2].

For most conditions and over-the-counter strengths, use is typically recommended for a short duration, often one to two weeks [1.7.2]. A healthcare provider might prescribe longer courses for chronic conditions, but this requires careful monitoring to mitigate potential side effects [1.2.1].

The Dangers of Prolonged Use: So, Can You Use Cortisone Cream Long Term?

Continuous, unsupervised long-term use of cortisone cream is strongly discouraged due to a range of potential local and, more rarely, systemic side effects [1.2.1, 1.2.4]. The risk increases with higher potency steroids, application to large areas of skin, use on thin-skinned areas (like the face or groin), and the use of occlusive dressings [1.2.4, 1.9.2].

Local Side Effects

The most common adverse effects occur on the skin where the cream is applied. These include:

  • Skin Atrophy (Thinning): This is the most frequent side effect, where the skin becomes fragile, transparent, and wrinkled [1.4.2, 1.8.4].
  • Striae (Stretch Marks): Prolonged use can cause permanent stretch marks, which may fade over time but do not disappear completely [1.2.1].
  • Perioral Dermatitis and Rosacea: Using topical steroids on the face can trigger or worsen acne-like breakouts and persistent redness around the mouth and nose [1.2.2, 1.8.1].
  • Hypopigmentation: Patchy loss of skin color can occur, which is particularly noticeable in individuals with darker skin tones [1.2.2].
  • Telangiectasias: The appearance of fine, dilated blood vessels on the skin's surface [1.9.2].

Topical Steroid Withdrawal (TSW)

Topical Steroid Withdrawal, also known as Red Skin Syndrome, is a potential consequence of stopping topical steroids after prolonged, frequent use [1.4.3]. Symptoms can be more severe than the original skin condition and include intense redness, burning, stinging, itching, and skin peeling [1.4.1, 1.4.4]. TSW can occur within days to weeks after discontinuing the medication and can be a debilitating condition that requires medical support to manage [1.4.2, 1.4.4].

Systemic Side Effects

Though rare, potent topical steroids can be absorbed into the bloodstream, especially when used over large areas or for extended periods, leading to systemic side effects [1.2.5]. These can include:

  • HPA Axis Suppression: The body's natural production of cortisol by the adrenal glands can be suppressed [1.2.4, 1.2.5].
  • Cushing's Syndrome: Symptoms can include weight gain, a rounded face, and high blood pressure [1.2.3, 1.2.5].
  • Hyperglycemia (High Blood Sugar): This is a risk, particularly for those with pre-existing diabetes [1.2.1].
  • Ocular Issues: Using potent steroids near the eyes can increase the risk of glaucoma and cataracts [1.2.3, 1.9.4].

Topical Corticosteroid Potency Comparison

Understanding the strength of a cortisone cream is crucial for safe use. Steroids are typically grouped into seven classes, with Class 1 being the strongest and Class 7 being the mildest [1.3.1].

Potency Class Example Generic Name Common Use & Duration Guidelines
Class 1 (Superpotent) Clobetasol Propionate 0.05% Severe dermatoses; use should be limited to <2 weeks.
Class 2 (Potent) Betamethasone Dipropionate 0.05% Severe eczema/psoriasis; use should be intermittent and monitored.
Class 3-5 (Mid-Strength) Triamcinolone Acetonide 0.1% Atopic dermatitis; suitable for moderate conditions, avoid on thin skin.
Class 6 (Mild) Desonide 0.05% Good for face, groin, and children; shorter-term use preferred [1.3.4].
Class 7 (Least Potent) Hydrocortisone 1% (OTC) Minor rashes, insect bites; generally safe for up to 1-2 weeks [1.3.1, 1.7.2].

Best Practices for Safe Application

To minimize risks, always follow your doctor's instructions or the product label. General best practices include:

  1. Wash Hands: Wash your hands before and after application, unless you are treating your hands [1.5.1].
  2. Apply a Thin Layer: Use only a small amount (often measured in "fingertip units") and apply a thin film only to the affected skin areas [1.5.1, 1.5.2].
  3. Rub in Gently: Smooth the cream into the skin in the direction of hair growth until it disappears [1.5.2].
  4. Avoid Broken Skin: Do not apply to cuts, scrapes, or infected skin unless directed by a doctor [1.5.1].
  5. Use for Prescribed Duration: Stop using the cream once the skin has improved. Do not use over-the-counter products for more than a week without consulting a doctor [1.5.2].
  6. Avoid Sensitive Areas: Do not use on the face, groin, or underarms unless specifically instructed by a healthcare professional [1.7.1]. The skin in these areas is thinner and absorbs more medication, increasing the risk of side effects [1.8.1].

Alternatives to Long-Term Cortisone Use

For chronic skin conditions, relying solely on cortisone is not a sustainable solution. Safer long-term management strategies include:

  • Emollients and Moisturizers: Liberal and frequent use of moisturizers helps restore the skin barrier, a key step in managing conditions like eczema [1.6.4].
  • Calcineurin Inhibitors: Prescription topicals like tacrolimus and pimecrolimus can treat inflammation without the steroid-related side effects, making them suitable for sensitive areas [1.6.2].
  • Phosphodiesterase-4 (PDE4) Inhibitors: Newer non-steroidal creams like crisaborole can also reduce inflammation in atopic dermatitis [1.10.2].
  • JAK Inhibitors: Topical medications like ruxolitinib are another class of non-steroidal treatment for certain inflammatory skin conditions [1.10.2].
  • Lifestyle and Environmental Changes: Identifying and avoiding personal triggers (allergens, irritants, stress) is fundamental to preventing flare-ups [1.6.4].

Conclusion

So, can you use cortisone cream long term? The evidence-based answer is generally no, not without significant risks and strict medical supervision. While these creams are invaluable for managing acute flare-ups of skin conditions, their long-term use can lead to serious side effects, including irreversible skin damage and topical steroid withdrawal [1.2.1, 1.2.2]. It is essential to use the lowest effective potency for the shortest possible duration. For chronic conditions, working with a dermatologist to develop a long-term management plan that incorporates steroid-sparing alternatives is the safest and most effective approach to maintaining skin health [1.10.2].


For more information from a trusted patient advocacy group, visit the National Eczema Association [1.11.4].

Frequently Asked Questions

If you buy hydrocortisone from a pharmacy or shop, you should not use it for more than one week without talking to your doctor. For most minor conditions, a few days to a week is sufficient [1.5.2, 1.7.2].

Early signs of TSW often appear days to weeks after stopping a topical steroid and include intense skin redness, a burning or stinging sensation, and itching that can be more severe than the original condition [1.4.1, 1.4.4].

You should not use cortisone cream on your face unless specifically prescribed and monitored by a doctor. The skin on the face is delicate and absorbs the medication more readily, increasing the risk of side effects like perioral dermatitis, acne, and skin thinning [1.8.1, 1.8.2].

Using cortisone cream for many months can lead to serious side effects, including permanent skin thinning (atrophy), stretch marks (striae), and a risk of topical steroid withdrawal when you stop. It can also, in rare cases, be absorbed into the blood and cause systemic issues [1.2.1, 1.2.2].

Yes, there are several non-steroidal alternatives. These include topical calcineurin inhibitors (like pimecrolimus and tacrolimus), PDE4 inhibitors (like crisaborole), and diligent use of emollients and moisturizers to repair the skin barrier [1.6.2, 1.10.2].

The difference is their strength. Mild creams, like hydrocortisone 1%, are available over the counter and are safer for short-term use on minor irritations [1.3.4]. Potent creams, like clobetasol, are prescription-only and are much stronger, carrying a higher risk of side effects and are reserved for severe conditions under medical supervision [1.3.1].

While rare, prolonged use of high-potency topical steroids over large areas can lead to systemic absorption. This can potentially cause side effects like high blood sugar, high blood pressure, and suppression of the adrenal glands [1.2.3, 1.2.5, 1.9.4].

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.