Terra-Cortril, which may contain polymyxin B, is a medication formulated for the topical treatment of inflammatory and bacterial infections in the eye, ear, and sometimes on the skin. The specific composition of Terra-Cortril can vary. Ophthalmic/otic versions often include oxytetracycline, hydrocortisone, and polymyxin B, while some topical skin ointments may contain only oxytetracycline and hydrocortisone. This information focuses on the use of formulations containing polymyxin B for ocular and auricular conditions, as well as general usage principles for related topical preparations.
Proper Application Techniques
Correct application is vital for the medication to reach the affected area effectively and to avoid contamination. Always wash your hands with soap and water before and after application.
For Eye Conditions (Ophthalmic Use)
Ointment Application To apply the eye ointment, follow these steps:
- Tilt your head back or lie down.
- Gently pull your lower eyelid down to create a small pocket.
- Squeeze a small amount of ointment into this pocket.
- Close your eye and blink gently to help distribute the medication.
- Avoid touching the tube's tip to any surface to prevent contamination.
Suspension (Drops) Application If using drops, follow these instructions:
- Shake the bottle well before each use to ensure the medication is evenly mixed.
- Tilt your head back.
- Pull your lower eyelid down to create a space.
- Instill the prescribed number of drops into the affected eye.
- Close your eye and apply gentle pressure to the inner corner for a brief period to aid absorption.
- Replace the dropper immediately after use.
For Ear Conditions (Otic Use)
Ointment and Suspension Application To apply the medication to the ear, follow these guidelines:
- Tilt your head sideways with the affected ear facing up.
- For ointment, instill a small quantity into the ear canal.
- For suspension, instill the prescribed number of drops into the affected ear.
- Keep your head tilted for a few minutes to allow the medication to settle.
Important Considerations and Warnings
Several warnings and precautions are important when using Terra-Cortril to ensure patient safety and treatment efficacy.
Infections and Masking Effects: Corticosteroids can suppress the inflammatory response, potentially masking or enhancing the spread of an existing infection. This medication should only be used for the specific bacterial infections for which it is prescribed. It should not be used for viral or fungal infections of the eye or ear.
Prolonged Use: Long-term use of ophthalmic corticosteroids can lead to serious adverse effects, including elevated intraocular pressure, which can damage the optic nerve and potentially lead to vision loss, and cataract formation. If treatment is extended, regular eye pressure monitoring may be necessary.
Hypersensitivity: This medication is contraindicated in individuals with a known hypersensitivity to any of its components, such as oxytetracycline, polymyxin B, or hydrocortisone. Allergic reactions are possible.
Pregnancy and Pediatric Use: Oxytetracycline should not be used in pregnant women, nursing mothers, or young children, as it may cause permanent tooth discoloration and affect bone development. Terra-Cortril is generally not recommended for children unless specifically directed by a doctor.
Contamination: Avoiding contamination of the applicator tip is essential to prevent secondary infections.
When to Seek Medical Advice: If irritation occurs or symptoms do not improve within a certain timeframe as advised by a healthcare professional, contact your doctor. If there is not a prompt favorable response, especially in ocular infections, discontinuation of the corticosteroid component might be necessary.
Comparison of Terra-Cortril Formulations
| Feature | Ophthalmic Ointment | Ophthalmic Suspension | Otic Ointment | Otic Suspension |
|---|---|---|---|---|
| Application Area | Eye (conjunctiva/cornea) | Eye (conjunctiva/cornea) | Ear (external ear canal) | Ear (external ear canal) |
| Mechanism of Action | Combats inflammation (hydrocortisone) and broad-spectrum bacterial infection (oxytetracycline & polymyxin B). | Combats inflammation (hydrocortisone) and broad-spectrum bacterial infection (oxytetracycline & polymyxin B). | Combats inflammation (hydrocortisone) and broad-spectrum bacterial infection (oxytetracycline & polymyxin B). | Combats inflammation (hydrocortisone) and broad-spectrum bacterial infection (oxytetracycline & polymyxin B). |
| Key Precaution | Avoid prolonged use due to glaucoma risk. | Shake well before use. | Do not use with perforated eardrum. | Do not use with perforated eardrum. |
| Common Side Effects | Blurred vision, temporary stinging/burning. | Temporary stinging or burning, increased tear production. | Local irritation, itching. | Local irritation, itching. |
Conclusion
Using Terra-Cortril polymyxin B correctly involves understanding its specific formulation and following the application instructions provided by a healthcare professional. Whether for an eye or ear infection, the methods for applying ointment or suspension differ significantly. Adhering to the correct technique, including maintaining proper hygiene, is critical for effective treatment and minimizing potential side effects. Due to the presence of a corticosteroid, prolonged use should be carefully monitored. Always consult a doctor for diagnosis and guidance on the correct use of this medication to ensure a safe and successful outcome.
For more detailed prescribing information, refer to the package insert provided by the manufacturer or an authoritative source like Drugs.com.
