What is Brezu (Procaterol)?
Brezu is a brand name for the medication procaterol hydrochloride, a selective beta-2 adrenergic receptor agonist. It works by stimulating specific receptors on the smooth muscles of the airways, causing them to relax and widen. This bronchodilating effect makes it easier for patients with respiratory obstructive diseases, such as asthma, chronic bronchitis, and pulmonary emphysema, to breathe. It is available as a syrup for oral administration.
Brezu for different patient populations
The correct dosage of Brezu varies significantly depending on the patient's age and the severity of their symptoms. Healthcare providers will determine the precise dose, but general guidelines are available for different patient populations:
- Adults: Information regarding adult administration is typically provided by a healthcare professional.
- Children 6 years and older: Information regarding administration for this age group is typically provided by a healthcare professional.
- Children under 6 years: Information regarding administration for younger children is typically provided by a healthcare professional.
It is essential to use an accurate measuring device, such as a dosing syringe or a specific measuring spoon, to ensure the correct volume of syrup is administered, especially for children. Never use a regular household spoon, as it is not an accurate measurement tool.
Important usage instructions and precautions
To use Brezu safely and effectively, patients must follow their doctor's instructions meticulously. The medication is a long-term maintenance treatment and is not intended for the rapid relief of acute respiratory distress.
How to properly take Brezu syrup
- Measure the dose: Using the provided measuring device, carefully measure the exact amount of syrup prescribed by your doctor.
- Take consistently: Take your dose around the same time each day to maintain a consistent level of medication in your body.
- Complete the course: Do not stop taking Brezu suddenly, even if you feel better. Abruptly discontinuing the medication can lead to a worsening of symptoms. Any changes to your treatment plan should be discussed with a doctor.
- Do not double up: If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.
Precautions and warnings
Before starting Brezu, inform your doctor about your complete medical history and all other medications you are taking, including over-the-counter drugs, vitamins, and herbal supplements. Certain conditions and medications require extra caution when taking Brezu:
Special Precautions:
- Cardiovascular Conditions: Patients with heart disease, hypertension (high blood pressure), or hyperthyroidism should use Brezu with caution due to the risk of palpitations, tachycardia (rapid heart rate), and other cardiac issues.
- Diabetes: Brezu can cause an increase in blood sugar levels, so diabetic patients should be carefully monitored.
- Drug Interactions: Medications such as other beta-2 agonists, xanthine derivatives, corticosteroids, and diuretics can increase the risk of adverse effects, including a significant decrease in serum potassium levels.
- Pregnancy and Lactation: Brezu should be used by pregnant or possibly pregnant women only if the expected benefit outweighs the potential risk. It is also advised to interrupt nursing while on this medication.
- Allergen Tests: Brezu may interfere with skin reactions during allergen tests. The drug should be withheld 12 hours prior to such testing.
Potential side effects
While Brezu is generally well-tolerated, some side effects may occur. Many people experience minimal or no side effects. Common side effects can include headache, tremor, palpitations, and nausea. However, some side effects can be more serious. Contact your doctor immediately if you experience any signs of a severe allergic reaction, such as swelling of the face, tongue, or throat, or difficulty breathing. Overdosage is also a concern and can lead to severe side effects like tachycardic arrhythmia and a significant decrease in serum potassium.
Brezu vs. Breztri: A comparison
It is important not to confuse Brezu (procaterol) with Breztri Aerosphere (budesonide/glycopyrrolate/formoterol), a combination inhaler for COPD. While both are used for respiratory conditions, they are fundamentally different in their ingredients, administration method, and indications.
| Feature | Brezu | Breztri Aerosphere |
|---|---|---|
| Active Ingredient(s) | Procaterol (beta-2 agonist) | Budesonide (ICS), Glycopyrrolate (LAMA), Formoterol (LABA) |
| Drug Class | Selective beta-2 agonist | Combination of Inhaled Corticosteroid (ICS), Long-Acting Muscarinic Antagonist (LAMA), and Long-Acting Beta2-Agonist (LABA) |
| Administration | Oral Syrup | Inhaled Aerosol |
| Indications | Bronchial asthma, chronic bronchitis, pulmonary emphysema, acute bronchitis | Maintenance treatment for Chronic Obstructive Pulmonary Disease (COPD) in adults |
| Primary Function | Bronchodilator to open airways | Combination therapy for inflammation and bronchodilation |
| Not for | Acute asthma episodes | Asthma, or sudden breathing problems |
| Requires rinsing mouth? | No | Yes, to prevent oral thrush from the steroid |
Conclusion
Understanding how to take Brezu correctly is essential for patients managing respiratory conditions like asthma and chronic bronchitis. As a long-term maintenance syrup, it must be taken exactly as prescribed by a healthcare provider, and it is crucial to understand that it is not a rescue medication for sudden breathing problems. Patients must be vigilant about potential side effects and disclose all health conditions and other medications to their doctor to ensure safe and effective treatment. Regular consultation with a healthcare professional ensures the medication is used properly and that any adverse reactions are promptly addressed. For reliable information and professional advice, refer to a source such as the MIMS Philippines Brezu Product Information or consult your prescribing physician.
