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Understanding Medications: What is Pill 25 Used For?

3 min read

In 2023, quetiapine, a common 'pill 25', was the 60th most prescribed medication in the United States with over 10 million prescriptions [1.3.2]. The question 'What is pill 25 used for?' is common, but the answer is complex as many drugs carry this identifier.

Quick Summary

The identifier 'pill 25' can refer to various medications, most commonly the atypical antipsychotic Quetiapine. It is also linked to Trazodone, Lamotrigine, and Topiramate, each with distinct uses and side effect profiles.

Key Points

  • Ambiguous Identifier: 'Pill 25' is not a unique identifier; it often refers to a 25 mg dosage of various drugs [1.2.5].

  • Most Common is Quetiapine: A peach or pink pill with a '25' is frequently Quetiapine, an antipsychotic for schizophrenia and bipolar disorder [1.2.1, 1.3.1].

  • Trazodone for Sleep: Trazodone at 25 mg is a common off-label prescription used to treat insomnia [1.4.3, 1.4.7].

  • Anticonvulsant Starters: Lamotrigine and Topiramate, used for epilepsy and other conditions, often start at a 25 mg dose [1.5.1, 1.6.2].

  • Serious Side Effects: All potential 'pill 25' medications have significant side effects; Lamotrigine carries a risk of severe rash [1.5.5].

  • Professional ID is Crucial: Due to the variety of possibilities, a pharmacist or doctor must be consulted for accurate pill identification.

  • Boxed Warnings: Quetiapine and Trazodone have FDA boxed warnings regarding increased suicidal thoughts in young adults [1.3.3, 1.4.4].

In This Article

The question, "What is pill 25 used for?" is a frequent query for those trying to identify medication. The number '25' on a pill can signify the dosage (25 mg) or be part of an imprint code. Because multiple medications fit this description, it's crucial to consider other features like color, shape, and additional scoring or lettering to make an accurate identification [1.2.1, 1.2.5]. Always consult a pharmacist or physician for definitive identification.

The Most Common Candidate: Quetiapine (Seroquel)

Often, a round, peach- or pink-colored pill with a '25' imprint is identified as 25 mg of Quetiapine Fumarate, commonly known by the brand name Seroquel [1.2.1, 1.2.5].

Primary Uses: Quetiapine is an atypical antipsychotic used to treat a variety of mental health conditions [1.3.1, 1.7.4]. It works by helping to restore the balance of natural chemicals (neurotransmitters) in the brain, such as dopamine and serotonin [1.3.1, 1.3.4].

  • Schizophrenia: It is used to manage symptoms of schizophrenia in adults and children aged 13 and older [1.3.7].
  • Bipolar Disorder: Quetiapine treats both manic and depressive episodes associated with bipolar disorder [1.3.2, 1.3.7]. It can be used as a standalone therapy or in conjunction with other mood stabilizers like lithium [1.3.2].
  • Major Depressive Disorder (MDD): It is often prescribed as an add-on treatment for MDD when other antidepressants have not been sufficiently effective [1.3.2, 1.3.6].

Off-Label Uses: Due to its sedating effects, quetiapine is sometimes prescribed off-label for insomnia [1.3.2]. However, this use is not recommended by many medical bodies due to potential side effects outweighing the benefits [1.3.2]. It's also used off-label for anxiety disorders and psychosis related to Parkinson's disease [1.3.2].

Common Side Effects: Common side effects include drowsiness, dizziness, dry mouth, constipation, increased appetite, and weight gain [1.3.3, 1.3.4]. More serious risks include an increased risk of suicidal thoughts in individuals under 25, neuroleptic malignant syndrome, tardive dyskinesia (uncontrolled movements), and metabolic changes like high blood sugar and cholesterol [1.3.1, 1.3.3].

Other Possibilities for 'Pill 25'

Several other common medications come in a 25 mg dosage and may be referred to as 'pill 25'.

Trazodone

Trazodone is an antidepressant classified as a serotonin antagonist and reuptake inhibitor (SARI) [1.4.1, 1.4.2].

  • Primary Use: Its primary FDA-approved use is for treating major depressive disorder [1.4.2].
  • Off-Label Use: Trazodone is widely used off-label at lower doses (25 mg to 100 mg) to treat insomnia due to its sedating effects [1.4.3, 1.4.7]. It is also sometimes used for anxiety [1.4.4].
  • Side Effects: Common side effects include drowsiness, dizziness, dry mouth, and headache [1.4.1]. A rare but serious side effect is priapism (a prolonged, painful erection) [1.4.4].

Lamotrigine (Lamictal)

Lamotrigine is an anticonvulsant medication also used as a mood stabilizer [1.5.1].

  • Primary Uses: It is used to treat certain types of seizures in epilepsy and as a maintenance treatment for bipolar I disorder to delay mood episodes like depression or mania [1.5.4, 1.5.7]. The initial dose is often 25 mg [1.5.1].
  • Side Effects: The most notable risk is a serious skin rash, including Stevens-Johnson syndrome, which can be life-threatening. The risk is highest when starting the medication or increasing the dose too quickly [1.5.1, 1.5.5]. Other common side effects include dizziness, headache, and nausea [1.5.5].

Topiramate (Topamax)

Topiramate is another anticonvulsant medication with different applications [1.6.3].

  • Primary Uses: It is used to prevent seizures in people with epilepsy and to prevent migraine headaches in adults [1.6.5, 1.6.7]. The starting dose is often 25 mg.
  • Side Effects: Common side effects include tingling sensations, fatigue, dizziness, loss of appetite, weight loss, and cognitive issues like difficulty with concentration or finding words ("brain fog") [1.6.2, 1.6.6]. It can also increase the risk of kidney stones [1.6.2].

Comparison of Common 'Pill 25' Candidates

Medication Primary Class Primary Approved Uses Common 25 mg Use Context
Quetiapine Atypical Antipsychotic Schizophrenia, Bipolar Disorder, add-on for Depression [1.3.2] Starting dose for mood disorders; sometimes for sleep [1.3.1, 1.3.2]
Trazodone Antidepressant (SARI) Major Depressive Disorder [1.4.2] Common off-label dose for insomnia [1.4.3, 1.4.7]
Lamotrigine Anticonvulsant / Mood Stabilizer Epilepsy, Bipolar I Disorder (maintenance) [1.5.1] Standard starting dose for slow titration [1.5.1]
Topiramate Anticonvulsant Epilepsy, Migraine Prevention [1.6.7] Standard starting dose for slow titration [1.6.2]

Conclusion

While a 'pill 25' is most frequently associated with Quetiapine for treating serious mental health conditions, it can also be Trazodone for sleep, or a starting dose of Lamotrigine or Topiramate for seizures, bipolar disorder, or migraines. Due to the wide range of potential medications and their serious effects, self-identification is risky. It is essential to have any unidentified medication verified by a healthcare professional, such as a pharmacist, who can use comprehensive pill identification databases to provide an accurate answer and ensure patient safety. Never take medication that is not prescribed to you.


For more detailed medication information, you can visit the FDA's drug information database.

Frequently Asked Questions

It might be. A round, peach-colored pill with a '25' imprint is often identified as 25 mg of Quetiapine Fumarate, the generic name for Seroquel. However, other medications also have this marking, so verification by a professional is necessary [1.2.1, 1.2.5].

Quetiapine 25mg is a common starting dose for treating conditions like bipolar disorder and schizophrenia. It is also frequently, though off-label, prescribed for its sedating effects to help with sleep [1.3.1, 1.3.2].

Some medications with a '25' marking, like low-dose Trazodone or Quetiapine, are prescribed for sleep [1.4.3, 1.3.2]. However, you should never take any prescription medication unless it has been prescribed specifically for you by a doctor for that purpose.

Lamotrigine has a serious risk of causing a life-threatening skin rash, including Stevens-Johnson syndrome. This risk is highest when starting the medication or when the dose is increased too rapidly [1.5.1, 1.5.5].

Based on common pill identifiers, 'pill 25' is not typically an opioid. The most common medications associated with this marking are antipsychotics (Quetiapine), antidepressants (Trazodone), or anticonvulsants (Lamotrigine, Topiramate) [1.2.1, 1.4.1, 1.5.1, 1.6.3].

Different medications, even with similar markings, have vastly different uses, side effects, and serious risks. Misidentifying and taking the wrong medication can lead to ineffective treatment, dangerous drug interactions, or severe adverse health events.

Pills with a '25' imprint can also be Exemestane (for breast cancer), Metoprolol (for high blood pressure), or Hydralazine (for high blood pressure), among others. The color, shape, and other markings are critical for accurate identification [1.2.2, 1.2.3, 1.2.5].

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.