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Understanding the Differences: What is the difference between a cortisone shot and an epidural shot?

5 min read

Cortisone is a powerful anti-inflammatory medication, but despite often being used interchangeably, a cortisone shot and an epidural are distinct procedures. Understanding what is the difference between a cortisone shot and an epidural shot is key to determining the appropriate treatment for your pain and inflammation issues.

Quick Summary

This article clarifies the distinction between a cortisone shot and an epidural injection, highlighting differences in injection site, medical purpose, and the specific conditions each procedure is designed to treat.

Key Points

  • Location Matters: The main distinction is the injection site. Cortisone shots target specific joints and tissues, while epidurals are administered exclusively into the epidural space of the spine.

  • Targeted Pain Relief: Cortisone shots address localized pain from conditions like arthritis and bursitis, whereas epidurals relieve radiating nerve pain (radiculopathy) caused by spinal issues.

  • Precision is Key for Epidurals: Due to the spinal location, epidural injections require fluoroscopy (live X-ray) for accurate and safe placement of the medication.

  • Same Drug, Different Delivery: Both procedures often use the same anti-inflammatory corticosteroid medication, but the delivery method and target area are based on the underlying condition.

  • Symptom Management, Not a Cure: Neither injection permanently fixes the underlying problem. They are used to manage inflammation and pain, facilitating other treatments like physical therapy.

In This Article

Both cortisone shots and epidural steroid injections are common medical procedures used to treat inflammation and manage pain. While they both often involve the same class of medication—corticosteroids—their application, target area, and purpose are fundamentally different. A cortisone shot is a general term for a localized steroid injection, while an epidural is a specific type of injection delivered to the spine. The best choice for a patient depends on the underlying cause of their pain and inflammation.

The Core Distinction: Location and Purpose

The most important distinction lies in the location of the injection. A standard cortisone shot can be administered into almost any inflamed joint, tendon, or bursa in the body, such as the knee, shoulder, or elbow. It is used to treat localized inflammation. In contrast, an epidural steroid injection is performed exclusively in the spine to deliver medication into the epidural space, which surrounds the spinal cord and nerve roots. Its purpose is to reduce inflammation around specific spinal nerves that are irritated or compressed, causing radiating pain.

What is a Cortisone Shot?

A cortisone shot is a minimally invasive procedure designed to alleviate pain and swelling by delivering a corticosteroid directly to an inflamed site. The medication works by suppressing the immune system's inflammatory response at the local level.

How is a cortisone shot administered?

  • Targeted Delivery: The shot is injected directly into the specific joint (e.g., knee arthritis), tendon (e.g., tennis elbow), or bursa (e.g., hip bursitis).
  • Optional Guidance: While some injections may be performed without guidance, a doctor may use an ultrasound to ensure accurate placement of the medication, particularly in smaller joints or complex areas.
  • Relief Timeline: Patients may experience immediate, temporary relief from an added anesthetic, with the full anti-inflammatory effect of the cortisone starting days later. Relief typically lasts from several weeks to several months.

Conditions treated by cortisone shots

Cortisone shots are effective for a wide range of inflammatory musculoskeletal conditions, including:

  • Arthritis: Especially inflammatory types like rheumatoid arthritis, but also used for osteoarthritis.
  • Bursitis: Inflammation of the small fluid-filled sacs that cushion joints.
  • Tendinitis: Inflammation of a tendon, like in the shoulder or elbow.
  • Plantar Fasciitis: Inflammation of the band of tissue connecting the heel to the toes.
  • Carpal Tunnel Syndrome: Injections can reduce inflammation around the median nerve in the wrist.

What is an Epidural Shot?

An epidural shot, more accurately called an epidural steroid injection (ESI), is a specialized procedure for treating pain that originates in the spine. The medication, which is a corticosteroid often mixed with a local anesthetic, is injected into the epidural space to soothe irritated and compressed nerve roots.

How is an epidural shot administered?

  • Spinal Location: The injection targets the epidural space, the area between the bony vertebrae and the dura mater, the sac protecting the spinal cord.
  • Image Guidance: To ensure precise and safe delivery, an epidural injection is always performed using fluoroscopy (a live X-ray). This allows the physician to visualize the needle's path and confirm the medication is flowing to the correct location.
  • Radiating Pain: The primary goal is to alleviate radiculopathy—pain that radiates from the spine into the arms, legs, or other areas—which is caused by pressure on a spinal nerve.

Conditions treated by epidural shots

ESIs are specifically used for conditions that cause nerve root compression and radiating pain. These include:

  • Herniated Discs: When the soft inner material of a disc pushes out and presses on a nerve.
  • Spinal Stenosis: The narrowing of the spinal canal, which can put pressure on nerves.
  • Sciatica: Pain that radiates along the sciatic nerve, from the lower back down the leg.
  • Degenerative Disc Disease: Pain resulting from wear and tear on the spinal discs.

Cortisone Shot vs. Epidural Shot: A Comparison

Feature Cortisone Shot (General) Epidural Shot (ESI)
Injection Site Specific joint, tendon, or bursa anywhere in the body (e.g., knee, shoulder, wrist). Epidural space surrounding the spinal cord and nerve roots in the back or neck.
Primary Purpose To reduce localized inflammation and pain in a specific area. To reduce inflammation of spinal nerve roots causing radiating pain (radiculopathy).
Targeted Conditions Arthritis, bursitis, tendinitis, plantar fasciitis, carpal tunnel syndrome. Herniated discs, spinal stenosis, sciatica, nerve root compression.
Guidance Technique May use ultrasound for accuracy, but sometimes given without imaging. Requires fluoroscopy (live X-ray) for precise and safe placement.
Symptom Type Treats a localized inflammatory condition causing pain and swelling. Treats nerve-related pain that often radiates from the spine.

Potential Side Effects

Both types of injections carry potential side effects, though serious complications are rare. Common side effects for both can include temporary pain or soreness at the injection site, a short-term increase in blood sugar for diabetics, and temporary facial flushing.

  • Cortisone Shot Side Effects: Potential side effects can also include tendon weakening or rupture with frequent use, skin thinning, and discoloration at the injection site.
  • Epidural Shot Side Effects: Serious but rare complications can include stroke, paralysis, or infection, which is why image guidance is crucial. Other potential side effects include headaches and nausea.

The Role of Each Treatment in Pain Management

The decision to use a cortisone shot or an epidural depends entirely on the source of the patient's pain. For pain isolated to a single joint due to arthritis or a tendon injury, a localized cortisone shot is the appropriate treatment. If the pain is radiating from the spine due to nerve compression, an epidural is necessary to deliver the medication directly to the affected nerve roots. In some cases, a cortisone shot might be used in the facet joints of the spine, but this is different from an ESI, which targets the epidural space.

Ultimately, neither injection is a cure for the underlying problem, but rather a tool to manage symptoms. They can provide significant relief, allowing patients to participate more effectively in physical therapy and other rehabilitative treatments. Your healthcare provider will conduct a thorough examination and use diagnostic tools to determine the best course of action.

Conclusion

While a cortisone shot and an epidural steroid injection both use corticosteroid medication to reduce inflammation, they are distinctly different procedures targeting different areas of the body. The primary difference lies in the injection's location and the specific medical purpose. A standard cortisone shot is for localized, non-spinal issues like arthritis or tendonitis, while an epidural shot is specifically for relieving nerve pain originating from the spinal column. The procedure for an epidural requires specialized image guidance to ensure precise delivery to the epidural space. Always consult with a medical professional to get an accurate diagnosis and determine which injection is right for your specific condition. The right treatment can provide significant pain relief and improve your quality of life.

For more information on different types of steroid injections, you can visit the Hospital for Special Surgery website.

Frequently Asked Questions

Cortisone shots are used to treat a wide variety of inflammatory conditions affecting joints, tendons, and bursae. These include arthritis (rheumatoid and osteoarthritis), bursitis, tendinitis, plantar fasciitis, and carpal tunnel syndrome.

A doctor would recommend an epidural shot when the pain is radiating from a nerve in the spine. Conditions like a herniated disc, spinal stenosis, or sciatica cause nerve root compression, and an epidural injection delivers the anti-inflammatory medication directly to the affected nerve roots in the spine's epidural space.

No, while both procedures involve injecting medication into the epidural space, the purpose and medication differ significantly. An epidural for childbirth is for anesthesia and pain blocking, while an epidural steroid injection uses a corticosteroid to reduce inflammation around spinal nerves.

Both types of shots often include a local anesthetic that provides immediate, though temporary, pain relief. The anti-inflammatory effect of the corticosteroid itself typically takes 24 to 72 hours to begin working in both cases, with full effect sometimes taking up to a week.

Yes. Most medical professionals recommend limiting cortisone and epidural injections to no more than three or four times per year in a given area. Frequent injections can potentially cause damage to surrounding tissues or bone density over time.

Common, minor side effects include temporary pain, soreness, facial flushing, or increased blood sugar levels. Serious complications like infection, nerve damage, or bleeding are rare but possible. Epidural injections carry a small risk of more severe neurological complications.

Epidural steroid injections (ESIs) always require image guidance, typically fluoroscopy, to ensure the medication is delivered accurately to the delicate epidural space. For general cortisone shots in peripheral joints, image guidance like ultrasound may be used for better accuracy but is not always required.

No, a cortisone shot will not fix or correct a herniated disc. An epidural steroid injection can reduce the inflammation and pain associated with a herniated disc, providing temporary relief, but it does not treat the underlying structural problem.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.