What is Deviry 10mg Tablet?
Deviry 10mg Tablet contains medroxyprogesterone acetate (MPA), a synthetic progestin that mimics the action of natural progesterone in the body. It is primarily used to treat disorders related to the female reproductive system where there is insufficient natural progesterone.
Primary Uses of Deviry 10mg Tablet
Deviry 10mg is prescribed for several gynecological conditions, with the specific treatment depending on the individual case.
1. Abnormal Uterine Bleeding
For irregular or excessive uterine bleeding not caused by other medical conditions, Deviry 10mg helps regulate the menstrual cycle by controlling the uterine lining's growth and shedding.
2. Amenorrhea
In cases where menstrual periods are absent due to hormonal imbalances (secondary amenorrhea), Deviry 10mg can induce menstruation by simulating normal hormonal changes.
3. Endometriosis
Deviry 10mg can help manage the symptoms of endometriosis, a condition where uterine-like tissue grows outside the uterus. It regulates hormone levels, reducing the growth of this tissue and alleviating associated pain.
4. Endometrial Hyperplasia Prophylaxis
Postmenopausal women using estrogen hormone replacement therapy may be at risk of endometrial hyperplasia, a thickening of the uterine lining. Deviry 10mg is used alongside estrogen therapy to prevent this and reduce the risk of uterine cancer.
How Deviry 10mg Works
Medroxyprogesterone acetate primarily works by binding to progesterone receptors. This action helps inhibit excessive growth of the uterine lining, regulate menstrual cycles, and reduce the growth of endometrial tissue outside the uterus.
Dosage and Administration
A healthcare provider determines the dosage and duration of Deviry 10mg based on the specific condition. Generally, the tablet is swallowed whole with water, can be taken with or without food at a consistent time daily, and the prescribed dose should not be altered without medical advice.
Important Precautions and Warnings
A thorough medical history should be discussed with a doctor before taking Deviry 10mg. It is contraindicated in certain situations, such as during pregnancy or for individuals with a history of breast cancer, active liver problems, blood clots, stroke, or undiagnosed vaginal bleeding. Caution is also advised for those with conditions like diabetes, hyperlipidemia, fluid retention, depression, asthma, epilepsy, or migraine.
Potential Side Effects
Common side effects of Deviry 10mg can include headache, nausea, breast tenderness, weight gain, irregular bleeding, hair loss, acne, dizziness, and mood swings. Serious side effects requiring immediate medical attention include severe headaches, leg or chest pain, sudden vision changes, jaundice, or severe allergic reactions.
Comparison Table: Deviry vs. Other Progestins
| Feature | Deviry (Medroxyprogesterone Acetate) | Natural Progesterone | Primolut N (Norethisterone) |
|---|---|---|---|
| Classification | Synthetic Progestin | Bioidentical Hormone | Synthetic Progestin |
| Effect | Stronger, more potent effects | Less potent, bioidentical | Varies by dose and indication |
| Primary Uses | Menstrual disorders, endometriosis, endometrial hyperplasia prophylaxis | Hormone replacement therapy, fertility support (depending on formulation) | Delaying periods, menstrual disorders |
| Key Difference | Induces periods for absent menses | Supports luteal phase, often used for HRT | Often used to delay periods |
| Formulations | Oral tablets, injections | Oral tablets (Prometrium), vaginal gels/suppositories | Oral tablets |
Conclusion
Deviry 10mg Tablet, a synthetic progestin, is effectively used for managing abnormal uterine bleeding, amenorrhea, endometriosis, and preventing endometrial hyperplasia. It works by mimicking natural progesterone to restore hormonal balance. However, due to potential side effects and contraindications, particularly regarding pregnancy, breast cancer, and blood clots, it should only be used under strict medical supervision. A healthcare provider will determine the appropriate dosage and duration of treatment. For comprehensive information on medroxyprogesterone, reliable resources such as the official Mayo Clinic page are available.
