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Understanding What Are the Side Effects of Zarbee's

4 min read

While marketed as containing “natural” ingredients and often perceived as a safer alternative to conventional medicines, it is critical to understand what are the side effects of Zarbee's, as potential risks and reactions are directly tied to the specific product’s formulation.

Quick Summary

Zarbee's products can cause side effects that vary by ingredient, such as drowsiness from melatonin or nausea. Severe reactions, including botulism in infants from honey and allergic responses, are also possible, so it is essential to check ingredients and follow usage instructions carefully.

Key Points

  • Product-Specific Side Effects: Side effects vary significantly between different Zarbee's products based on their ingredients, such as melatonin or honey.

  • Infant Botulism Risk: Honey-based Zarbee's products are dangerous for infants under 12 months due to the risk of infant botulism.

  • Melatonin Side Effects: Melatonin-containing products can cause drowsiness, dizziness, headaches, and in some children, behavioral changes and bedwetting.

  • Allergic Reaction Potential: Allergic reactions to honey, herbal extracts, or other ingredients can occur, sometimes severely.

  • Overdose is Still Dangerous: Even without traditional active drug ingredients, an overdose of Zarbee's products can cause serious symptoms, including confusion and seizures, and requires immediate medical attention.

  • Not a Medical Treatment: Zarbee's products are supplements, and they are not intended to diagnose, treat, cure, or prevent any disease.

  • Regulatory History: The brand has faced past scrutiny from the FDA regarding its marketing claims, underscoring the need for consumer diligence.

In This Article

Zarbee's has become a popular brand for parents and adults seeking wellness products with ingredients inspired by nature. However, the term "natural" does not guarantee the absence of side effects. The potential reactions to Zarbee's products depend entirely on the specific formula and active ingredients within each item. From mild issues like drowsiness to more serious concerns such as infant botulism, a thorough understanding of the product before use is essential for safety.

Ingredient-Specific Side Effects

The most common and significant side effects associated with Zarbee's products are linked to their key ingredients. Since the brand offers a variety of formulations for different needs, it is crucial to check the specific product label.

Side Effects of Honey

  • Infant Botulism: For infants under 12 months, honey poses a significant risk of infant botulism. This is due to bacterial spores that can be present in honey and, while harmless to older children and adults, can cause a dangerous illness in a baby's underdeveloped digestive system. For this reason, Zarbee's infant cough products (for babies aged 12-24 months) utilize agave instead of honey.
  • Allergic Reactions: Although rare, some individuals may be allergic to honey itself, which can cause reactions ranging from hives and itching to more severe swelling.

Side Effects of Melatonin

Zarbee's offers a line of sleep aid products containing melatonin. Common side effects associated with melatonin supplementation include:

  • Drowsiness: While intended to promote sleep, lingering drowsiness or grogginess the following day is a common complaint.
  • Dizziness and Headaches: Some users may experience headaches or a sensation of dizziness.
  • Gastrointestinal Upset: Nausea and other stomach issues can occur.
  • Behavioral Changes in Children: In some cases, mood and behavior changes, such as anxiety, irritability, or confusion, have been reported.
  • Bedwetting: Melatonin use in children has been associated with an increased risk of bedwetting.

Side Effects of Herbal and Vitamin Ingredients

Many Zarbee's products contain herbal extracts like elderberry, ivy leaf, and chamomile, along with vitamins like C and D. While generally considered safe, some considerations apply:

  • Allergic Reactions: Individuals with sensitivities to plants in the Asteraceae family, such as ragweed, should exercise caution with herbal extracts, as allergic reactions are possible.
  • Overdosing on Vitamins: Excessive intake of vitamins and minerals like zinc, found in immune support products, can lead to side effects like stomach upset and nausea.
  • Questionable Efficacy: It is important to note that as supplements, the effectiveness of some herbal ingredients is not always supported by the same rigorous clinical testing as regulated medications.

Common vs. Serious Side Effects

Common, Less Severe Side Effects (often temporary):

  • Drowsiness or dizziness
  • Nausea or stomach upset
  • Headache
  • Change in bowel habits, such as constipation (possible with certain ingredients)

Serious Side Effects (seek immediate medical attention):

  • Allergic Reactions: Symptoms such as rash, itching, hives, or swelling of the face, lips, tongue, or throat.
  • Infant Botulism: Constipation, poor feeding, and weakness in infants under 1 year old who have ingested honey.
  • Overdose Symptoms: Severe drowsiness, agitation, confusion, hallucinations, or seizures can occur with overdose of certain product ingredients, such as melatonin.
  • Mood or Behavior Changes: Anxiety, confusion, irritability, or other significant mood shifts, particularly with melatonin use.

Comparison of Zarbee's Product Types and Risks

Product Type Key Ingredients Potential Side Effects & Risks Primary Target Audience
Children's Cough Syrup w/ Honey Dark Honey, Ivy Leaf Extract Infant botulism risk (under 1 yr), mild GI upset Children 12 months+
Baby Cough Syrup w/ Agave Agave, Zinc Questionable efficacy compared to placebo, mild GI upset Babies 12-24 months
Children's Melatonin Melatonin, Chamomile Drowsiness, dizziness, nausea, headaches, bedwetting, behavioral changes Children 2+ (follow label)
Adult Immune Support Gummies Elderberry, Zinc, Vitamins Allergic reaction risk (rare), GI upset if overdosed Adults & Children 12+

Important Considerations for Zarbee's Users

Usage in Specific Populations

  • Infants under 12 months: Avoid all honey-containing products due to the risk of infant botulism. Consult a pediatrician before giving any supplement to a baby.
  • Pregnant or Nursing Women: Advise talking with a doctor before using any Zarbee's product.
  • Individuals with Pre-existing Conditions: If taking other medications or being treated for a medical condition, consult a doctor to ensure safety and avoid potential interactions.

Overdose Precautions

While many Zarbee's products are drug-free, an overdose can still cause serious symptoms, especially with ingredients like melatonin or menthol found in some non-Zarbee's cough drops. Following dosage instructions is critical. If you suspect an overdose, contact a poison control center or seek immediate medical help.

Regulatory Scrutiny and Recalls

  • FDA Warning Letter: In 2014, the FDA issued a warning letter to Zarbee's regarding their marketing claims, which were deemed too close to medical claims for a supplement. The company has since revised its advertising.
  • Product Recalls: In June 2025, several news outlets reported on a recall involving a batch of Zarbee's melatonin solution, citing potential bacterial contamination. This highlights the importance of staying informed about specific product recalls, even for "natural" brands. There has also been confusion with other recalls, such as a separate, unrelated recall of Little Remedies Honey Cough Syrup for bacterial risk.

Conclusion

While Zarbee's products are popular and generally well-tolerated, they are not entirely free of side effects or risks. The phrase "natural ingredients" does not substitute for caution, especially when considering products for infants or children. The specific side effects of Zarbee's are highly dependent on the product's formulation, particularly whether it contains honey, melatonin, or other active herbal components. To ensure safety, always read the product label carefully, follow the recommended dosage, and, most importantly, consult a healthcare professional before administering any new supplement, particularly for sensitive populations like infants and pregnant individuals.

Frequently Asked Questions

No, Zarbee's products are not completely safe for all infants. Honey-based products are dangerous for babies under 12 months due to the risk of infant botulism. Always check the specific product label for age recommendations and consult a pediatrician before use.

Yes, some users and medical reports indicate that melatonin can cause mood and behavioral changes in children, including irritability, nervousness, or confusion. If you notice these symptoms, discontinue use and speak with a healthcare provider.

If you suspect an overdose, especially if symptoms like severe drowsiness, agitation, or confusion are present, call a poison control center or emergency services immediately. Follow their instructions and be prepared to provide information on the product and amount ingested.

No, you should not give honey-based Zarbee's cough syrup to a child under 12 months of age because of the risk of infant botulism. The brand makes specific agave-based formulas for infants over 12 months.

Yes, it is possible to have an allergic reaction to ingredients in Zarbee's products, such as honey or certain herbal extracts. The product labels carry warnings for potential allergies, including sensitivities to the Asteraceae family (like ragweed). Symptoms may include rash, itching, or swelling.

Yes, in June 2025, a recall was reported for a batch of Zarbee's melatonin solution due to potential microbial contamination. It's crucial to check for recent recalls involving the specific product you use.

Not necessarily. While marketed as containing natural ingredients, a 2021 class action lawsuit alleged that some Zarbee's cough syrup products contained non-natural, synthetic ingredients, such as certain vitamins and zinc compounds. The brand is also regulated as a supplement, not a drug, so it's wise to review the full ingredient list.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.