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Understanding What is the Use of Searle Tablet: A Guide to Searle-Branded Medications

3 min read

The pharmaceutical company G.D. Searle & Company, known for pioneering the first female birth control pill, was acquired by Monsanto and later by Pfizer. Due to its history, many different medications manufactured under the Searle brand carry the company's imprint, leading to confusion when someone asks, 'What is the use of Searle Tablet?' The answer is not straightforward, as the name refers to a variety of drugs with distinct uses and active ingredients.

Quick Summary

Searle is a pharmaceutical brand, not a single medicine, and multiple tablets with a Searle imprint serve different medical purposes. These can include treating stomach ulcers, managing arthritis pain, preventing motion sickness, and controlling birth, each with specific active ingredients and safety profiles.

Key Points

  • Searle is a Brand, Not a Single Drug: Many different tablets with various uses were produced by the pharmaceutical company G.D. Searle, which is now a subsidiary of Pfizer.

  • Misoprostol Tablets (Cytotec): A Searle-branded tablet containing misoprostol, used to prevent NSAID-induced ulcers, with off-label uses for labor induction and abortion.

  • Diclofenac/Misoprostol Tablets (Arthrotec): Another Searle tablet combining an NSAID with misoprostol to treat osteoarthritis and rheumatoid arthritis.

  • Specialized Uses: Other Searle-branded tablets include Lomotil for diarrhea, Gravinate for motion sickness, and Demulen as a birth control pill.

  • Check the Imprint: To identify the use of a specific Searle tablet, one must check the full imprint, color, and shape, then use a pill identifier or consult a healthcare professional.

  • Pregnancy Warning: Certain Searle tablets, like Cytotec and Arthrotec, are contraindicated in pregnancy due to the misoprostol component and can cause severe harm.

In This Article

The question 'What is the use of Searle Tablet?' stems from a common misconception. Searle is the name of a historic pharmaceutical company, now a subsidiary of Pfizer, that produced a wide range of medications. Therefore, a tablet bearing the "Searle" imprint is not a single drug, but one of several different products, each with its own active ingredients and medical application. To determine a specific tablet's use, one must identify the additional markings, color, and shape, as many different drugs have carried the Searle name over the years.

A Clarification of Searle Imprints and Medications

Several distinct medications have historically been or are currently associated with the Searle name. Understanding these specific products is essential to answering the query correctly. A single tablet with a Searle marking may be an anti-ulcer medication, an anti-inflammatory drug for arthritis, or a contraceptive.

Cytotec (Misoprostol)

One of the most well-known Searle products is Cytotec, which contains the active ingredient misoprostol.

  • Primary Use: Cytotec is officially indicated to prevent gastric (stomach) ulcers in patients who are taking nonsteroidal anti-inflammatory drugs (NSAIDs) for conditions like arthritis. Misoprostol works by reducing stomach acid and protecting the stomach lining.
  • Off-label Uses: This drug is also widely used for several off-label purposes, including inducing labor and medical abortion.
  • Important Warning: Cytotec carries a significant risk and is contraindicated in pregnant women, as it can cause miscarriage, premature labor, and birth defects.

Arthrotec (Diclofenac/Misoprostol)

Arthrotec is another Searle product that combines the NSAID diclofenac with misoprostol.

  • Primary Use: This combination tablet is used to treat the symptoms of osteoarthritis and rheumatoid arthritis. The diclofenac component reduces pain and inflammation, while the misoprostol helps protect the stomach from the ulcer-causing effects of diclofenac.
  • Imprints: Tablets with the imprint "SEARLE 1421 AAAA 75" or "SEARLE 1411 AAAA 50" correspond to different strengths of Arthrotec.
  • Pregnancy Warning: Like Cytotec, Arthrotec is also unsafe for use during pregnancy due to the misoprostol component.

Lomotil (Diphenoxylate/Atropine)

Lomotil, an antidiarrheal medication, was also developed by Searle.

  • Primary Use: This tablet is used to treat diarrhea.
  • Imprint: The imprint "SEARLE 61" identifies a version of Lomotil.
  • Classification: It is considered a controlled substance due to its potential for abuse, unlike many other Searle products.

Other Searle Medications

  • Gravinate (Dimenhydrinate): Marketed by Searle, this tablet is used for motion sickness, nausea, and vomiting.
  • Flagyl ER (Metronidazole): The imprint "SEARLE 1961 FLAGYL ER" corresponds to a version of this antibiotic used for bacterial infections.
  • Demulen (Ethinyl Estradiol/Ethynodiol Diacetate): A birth control pill once produced by Searle with the imprint "P SEARLE".

Comparison of Common Searle-Branded Tablets

Brand Name (Searle Imprint) Active Ingredient(s) Primary Medical Use Key Precautions Potential Side Effects
Cytotec (SEARLE 1451/1461) Misoprostol Prevent NSAID-induced ulcers Contraindicated in pregnancy; prescription only Diarrhea, abdominal pain, headache
Arthrotec (SEARLE 1411/1421) Diclofenac and Misoprostol Osteoarthritis and rheumatoid arthritis Contraindicated in pregnancy; prescription only Diarrhea, abdominal pain, digestive issues
Lomotil (SEARLE 61) Diphenoxylate and Atropine Diarrhea Controlled substance; potential for abuse Drowsiness, dizziness, dry mouth
Gravinate (Searle Brand) Dimenhydrinate Motion sickness, nausea, vomiting Can cause drowsiness; dosage varies Drowsiness, dry mouth, blurred vision

Steps to Identify a Specific Searle Tablet

If you have a tablet with a Searle imprint and need to know its purpose, follow these steps:

  1. Examine the imprint: Look for all letters, numbers, and symbols on the tablet. A single "SEARLE" is not enough.
  2. Note the physical characteristics: Record the pill's color, shape (e.g., round, oval, six-sided), and size.
  3. Use a reliable pill identifier tool: Websites like Drugs.com or Medscape have comprehensive databases where you can input the details to identify the specific medication.
  4. Consult a healthcare provider: For safety, always confirm the medication with a doctor or pharmacist. Never take an unknown tablet without professional advice.

Conclusion

In summary, there is no single medication called 'Searle Tablet'. The name 'Searle' is a legacy brand name that appears on multiple distinct prescription drugs, including Cytotec for ulcers and Arthrotec for arthritis. A specific tablet's use depends entirely on its individual imprint and active ingredients. To ensure safety and accuracy, it is crucial to use a pill identifier and consult a healthcare professional. For more detailed information on specific medications, refer to authoritative sources such as MedlinePlus.

Disclaimer

This article provides general information and is not a substitute for professional medical advice. Always consult a healthcare provider for a diagnosis and treatment plan before taking any medication.

Frequently Asked Questions

No, Searle is a pharmaceutical brand, not a single medicine. The company produced many different tablets with a Searle imprint, each with a different active ingredient and medical purpose.

Cytotec, containing misoprostol, is used to prevent stomach ulcers in patients taking NSAIDs for conditions like arthritis. It is also used off-label for labor induction and medical abortion.

Arthrotec is a tablet containing both diclofenac and misoprostol, and is used to treat osteoarthritis and rheumatoid arthritis. The misoprostol helps protect against stomach ulcers caused by the diclofenac.

A tablet with the imprint 'SEARLE 61' is identified as Lomotil, a medication used to treat diarrhea.

No, you should not assume all Searle tablets are for pain relief. For example, some are for diarrhea (Lomotil) or ulcer prevention (Cytotec). Always confirm the specific medication and its use with a healthcare professional.

Many Searle-branded tablets, particularly those containing misoprostol (like Cytotec and Arthrotec), are dangerous and contraindicated during pregnancy as they can cause miscarriage or birth defects.

To identify a specific Searle tablet, use a reliable online pill identifier tool, noting all markings, color, and shape. Always consult a healthcare professional for accurate identification and advice.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.