Understanding What is the Vitaran Injection Technique?

October 7, 2025 •

4 min read

Over 89% of patients in clinical studies have shown improvement in skin elasticity after a course of Vitaran treatment, which is why understanding what is the Vitaran injection technique is crucial for practitioners. This advanced polynucleotide injectable uses precise methods, like microdroplets or a cannula, to deliver bio-stimulating effects deep within the skin.

Quick Summary

Vitaran, a polynucleotide injectable derived from trout DNA, can be administered using a fine-needle microdroplet technique for superficial concerns or a cannula for deeper dermal layers, stimulating collagen and elastin for skin rejuvenation.

Key Points

Microdroplet Technique: Involves superficial injections with a fine needle in a grid pattern to target fine lines and crepey skin.
Cannula Technique: Utilizes a blunt-ended cannula for deeper injection and broader distribution, ideal for larger areas and minimising bruising.
Polynucleotide Action: Vitaran uses purified trout DNA to stimulate the body's natural production of collagen and elastin for long-term regeneration.
Two Product Variants: Vitaran I is specifically formulated for the under-eye area, while Vitaran II is designed for larger areas like the face, neck, and hands.
Minimal Downtime: Most side effects, like temporary blebs, redness, and swelling, resolve quickly, with minimal post-treatment restrictions.
Contraindications: Vitaran is not suitable for pregnant or breastfeeding individuals, those with a fish allergy, or patients with certain autoimmune conditions or active infections.
Structured Treatment Plan: For best results, a course of initial treatments is recommended, followed by periodic maintenance sessions.

What Are Vitaran Polynucleotides?

Vitaran is a bio-stimulating injectable solution containing polynucleotides (PN) derived from purified fragments of trout DNA. This innovative product works at a cellular level, stimulating fibroblasts to produce more collagen and elastin. Unlike traditional skin boosters that primarily focus on hydration, Vitaran actively aids in tissue regeneration, repair, and overall skin revitalisation. The Vitaran line includes two main products: Vitaran I for the delicate periorbital (under-eye) area and Vitaran II for larger treatment areas like the face, neck, and hands. Its regenerative properties make it particularly effective for addressing signs of aging, scars, and general skin dullness.

The Vitaran Injection Technique: A Comprehensive Guide

The Vitaran injection technique is not a single, standardized approach but rather a set of methods a qualified practitioner can use depending on the treatment area and desired outcome. The two primary techniques are the microdroplet method and the cannula method.

Microdroplet Technique (Mesotherapy)

This technique involves using a very fine, short needle, typically a 34G 4mm needle, to administer tiny, superficial injections. The procedure follows a grid-like pattern across the treatment area, with injection points spaced about 1.5-2cm apart.

Best for:

Fine lines and wrinkles
Crepey skin
Small, precise areas, such as the under-eye (periorbital) region
Superficial skin concerns

Procedure Steps:

Numbing: A topical anaesthetic cream is often applied to minimise discomfort.
Injection: The practitioner injects a small amount superficially into the epidermis at each grid point.
Post-Treatment: The treatment area may have tiny bumps, known as blebs, which are normal and will disperse within a few hours.

Cannula Technique

For deeper, more widespread treatment, a practitioner might use a blunt-ended cannula, such as a 25g 50mm, to inject the product. This method is less invasive, as it requires fewer entry points, and can minimize bruising and swelling.

Best for:

Larger areas like the cheeks, neck, and décolletage
Deeper skin layers
Patients with a higher risk of bruising
Treating mild to moderate skin laxity

Procedure Steps:

Entry Point: A small entry point is made with a needle to allow the cannula to pass through.
Injection: The cannula is inserted and guided under the skin, where the product is delivered in a linear-retrograde or fanning motion.
Distribution: The cannula allows for a smooth, even distribution of the polynucleotide solution over a wider area through a single entry point.

A Step-by-Step Vitaran Treatment Journey

Here is a general outline of what a patient can expect during their Vitaran treatment process:

Initial Consultation: A practitioner assesses the client's skin, discusses goals, and determines the most suitable technique and product (Vitaran I or II). They also review any contraindications, such as a fish allergy or pregnancy.
Preparation: The skin is thoroughly cleansed, and a topical numbing cream is applied to enhance patient comfort.
Administration: The chosen injection technique is performed, with the total duration depending on the size of the treatment area.
Aftercare Instructions: The practitioner provides specific aftercare guidelines, which typically include avoiding strenuous exercise, alcohol, and makeup for 24-48 hours. A cold compress may be recommended for any mild swelling.
Treatment Course: Most clients require an initial course of sessions for optimal results.
Maintenance: Periodic maintenance sessions are often recommended to sustain the rejuvenating effects.

Comparison: Vitaran vs. Traditional Skin Boosters


Feature	Vitaran Polynucleotides	Traditional HA Skin Boosters
Mechanism	Stimulates fibroblasts to produce collagen and elastin; promotes cellular regeneration.	Primarily provides deep hydration by injecting a high concentration of hyaluronic acid (HA).
Source	Purified DNA fragments from trout.	Typically synthetic or bio-fermented hyaluronic acid.
Targeted Effects	Addresses long-term skin health, elasticity, regeneration, and fine lines.	Provides immediate hydration and a temporary 'glow'.
Treatment Focus	Regenerative therapy at a cellular level, offering longer-lasting, more profound results.	Hydration, volumisation, and general skin texture improvement.
Treatment Areas	Face, neck, décolletage, hands, and under-eyes (Vitaran I).	Similar areas, but Vitaran has a specific formulation for the delicate under-eye area.
Longevity	Results can last following a course of treatment.	Typically shorter duration.

Who is Vitaran For? Contraindications and Considerations

Vitaran is particularly suitable for individuals seeking deeper, more long-term skin rejuvenation rather than just superficial hydration. It is often recommended for patients aged 30 and over who are showing early signs of aging. However, certain conditions and allergies may prevent a patient from undergoing this treatment.

Contraindications include:

Pregnancy or breastfeeding
Known allergy to fish or other ingredients
Active skin infections or inflammation in the treatment area
Certain autoimmune diseases
History of keloid scarring
Use of blood-thinning medications

A thorough consultation is essential to ensure patient suitability and safety. The practitioner must have the appropriate training and certification to administer this treatment.

Conclusion

The Vitaran injection technique offers a powerful, regenerative approach to skin revitalisation that goes beyond simple hydration. By leveraging the bio-stimulating properties of polynucleotides, practitioners can use a variety of precise injection methods, including microdroplets for superficial treatments and cannulas for deeper work, to achieve remarkable results. The versatility of the technique, combined with the proven efficacy of the Vitaran product range, positions it as a leading solution for addressing cellular-level skin damage and promoting long-lasting rejuvenation. For licensed professionals seeking deeper understanding and advanced application, authoritative guides are available from reputable industry sources such as Fox Pharma, which offers comprehensive training materials and product information.

Frequently Asked Questions

Vitaran is a polynucleotide injectable that regenerates skin from a cellular level by stimulating collagen and elastin production, whereas traditional skin boosters typically use hyaluronic acid to provide hydration and a temporary glow.

Discomfort is typically minimal. A topical numbing cream is often applied before the procedure to reduce any sensation. Most patients only feel a light pinch or sting during the injections.

The small blebs that appear at the injection sites are normal and usually disperse within a few hours. In some cases, it may take up to 24-48 hours for them to completely subside.

Vitaran I is indicated for the sensitive periorbital (under-eye) area, while Vitaran II is used for larger areas such as the full face, neck, décolletage, and hands.

For optimal results, a course of initial treatments is recommended, with each session spaced appropriately. Maintenance treatments are then advised periodically.

For at least 24-48 hours after treatment, you should avoid strenuous exercise, excessive heat (like saunas or sunbathing), alcohol, and touching or massaging the treated area.

Yes, Vitaran can often be used in combination with other treatments. Some protocols suggest administering Vitaran prior to other dermal fillers or treatments to enhance overall results.