What is Aliseryl WS? A Combination Veterinary Treatment
Aliseryl WS is a well-established veterinary product known for its dual-action formula. As a water-soluble powder, it offers a practical and efficient way to deliver a mix of broad-spectrum antibiotics and supplementary vitamins to farm animals through their drinking water. The strategic combination of active ingredients targets multiple bacterial strains while the added vitamins support the animal's overall health and physiological functions. This makes it a valuable tool for modern livestock and poultry management.
The Pharmacological Breakdown of Aliseryl WS
Aliseryl WS's efficacy stems from its comprehensive list of active components. The product contains four key antibiotics, each targeting different aspects of bacterial infection, alongside a vital mix of vitamins for nutritional support.
- Antibiotic Components:
- Colistin Sulphate: A polymyxin antibiotic with bactericidal action, effective against Gram-negative bacteria such as E. coli, Haemophilus, and Salmonella species. Since it is poorly absorbed orally, its action is primarily localized to gastrointestinal infections.
- Oxytetracycline Hydrochloride: A tetracycline antibiotic that is bacteriostatic, meaning it inhibits bacterial growth. It targets a broad range of both Gram-positive and Gram-negative bacteria, including Bordetella, Chlamydia, Mycoplasma, Pasteurella, and Staphylococcus species.
- Erythromycin Thiocyanate: A macrolide antibiotic with bacteriostatic action, particularly effective against Gram-positive bacteria like Staphylococcus and Streptococcus species.
- Streptomycin Sulphate: An aminoglycoside antibiotic with bactericidal activity, primarily targeting Gram-negative bacteria such as E. coli, Klebsiella, and Salmonella species, as well as Mycoplasma.
- Vitamin Components:
- A full spectrum of vitamins, including A, D₃, E, B-complex vitamins ($B₁, B₂, B₆, B₁₂$), C, and K₃, is included. These vitamins are crucial for supporting numerous physiological functions and helping animals cope with the stress of disease and recovery.
Applications and Target Animals
Aliseryl WS is indicated for a broad range of applications across several species of farm animals.
Infections:
- Gastrointestinal infections: Targeting bacteria like E. coli and Salmonella that cause intestinal issues.
- Respiratory tract infections: Such as those caused by Mycoplasma or Bordetella.
- Urinary tract infections: Effectively treating a variety of bacteria affecting the urinary system.
Performance and Health Support:
- Growth promotion: The formula, particularly with its antibiotic and vitamin content, is known to help stimulate animal growth.
- Improved feed conversion: By maintaining gut health and boosting overall well-being, the product helps animals get more nutrients from their feed.
- Increased egg production: For poultry, it can help boost egg-laying performance.
- Stress and disease support: The vitamin package helps animals endure periods of illness or environmental stress.
Target Species:
- Poultry (chickens, pigeons, etc.)
- Swine (pigs)
- Calves (pre-ruminant)
- Sheep and Goats
Dosage, Administration, and Withdrawal Times
Proper administration is critical for efficacy and safety. Aliseryl WS is given orally via drinking water.
- Dosage for Swine and Poultry:
- Treatment: 1 kg of Aliseryl WS per 1,000 litres of drinking water for 5-7 days.
- Prevention: 1 kg of Aliseryl WS per 2,000 litres of drinking water for 5-7 days.
- Dosage for Calves, Sheep, and Goats:
- Treatment: 1 gram per 5 kg of body weight for 5-7 days. This is intended only for pre-ruminant animals.
Withdrawal Times:
- Meat: 7 days. Animals should not be slaughtered for human consumption within this period.
- Eggs: 1 day. Eggs laid within this period should not be used for human consumption.
Comparison with Other Antibiotic Treatments
A comparative study on young chickens demonstrated the effectiveness of Aliseryl WS in treating colibacteriosis when compared to a control group without treatment.
| Feature | Aliseryl WS | Oflosan | Control (No Treatment) |
|---|---|---|---|
| Survival Rate (Young Chickens) | 86% | 100% | 53% |
| Live Weight Increase | 125.8% | 127.5% | 78.5% |
Data adapted from a study comparing treatments for colibacteriosis in young chickens. While Oflosan showed a higher survival rate in this specific instance, Aliseryl WS still provided a significant improvement over the control group, showcasing its potential as a viable treatment option.
Contraindications and Safety Precautions
It is important to follow all label directions and safety guidelines when using Aliseryl WS. The product should not be administered to animals with known hypersensitivity to any of the active antibiotics (tetracyclines, macrolides, colistin, or aminoglycosides). Animals with severely impaired renal or hepatic function are also contraindicated. The concurrent use of certain other medications, such as penicillins, cephalosporins, quinolones, and cycloserine, should be avoided. There are no expected undesirable side effects if the prescribed dosage regimen is followed correctly.
Conclusion
Aliseryl WS is a multifaceted veterinary product, combining broad-spectrum antibiotics with essential vitamins to provide a robust treatment for bacterial infections and a supplement to improve animal health and productivity. Its primary uses revolve around treating gastrointestinal, respiratory, and urinary tract infections in poultry and other livestock, while also promoting growth, egg production, and feed conversion efficiency. The inclusion of vitamins helps animals cope with stress, making it a comprehensive solution for periods of disease. Responsible use, including adhering to proper dosage and withdrawal times, is paramount for ensuring both animal and human health.
For more detailed information, consult the product website for specifics on administration and usage: https://www.interchemie.com/veterinary-medicines/aliseryl-ws.
