Skip to content

What are the benefits of blueberry eye drops? A Scientific Review

4 min read

A 2024 study in the Women's Health Study found that women consuming one or more servings of blueberries per week had a significantly reduced risk of developing total age-related macular degeneration (AMD) [1.4.4]. This raises the question: what are the benefits of blueberry eye drops, and do they deliver the same power directly to the eye?

Quick Summary

Investigates the claimed benefits of blueberry eye drops, separating the proven effects of dietary blueberry consumption on eye health from the unsubstantiated and risky nature of topical, non-approved eye drop formulations.

Key Points

  • Dietary Benefits: Consuming blueberries is linked to a lower risk of age-related macular degeneration (AMD) and may protect against cataracts due to their antioxidant content [1.2.3, 1.4.4].

  • Anthocyanins are Key: The active compounds, anthocyanins, are absorbed through diet and delivered to the eyes via the bloodstream, where they provide protective effects [1.4.3].

  • No FDA Approval: Blueberry eye drops are not approved by the FDA. The agency warns against using any unapproved eye drops [1.5.5].

  • Serious Safety Risks: Unregulated eye drops pose a high risk of bacterial contamination, which can lead to severe eye infections, vision loss, or even blindness [1.6.1, 1.6.3].

  • Lack of Evidence: There is no credible scientific evidence to support the claims that applying blueberry extract topically via eye drops is safe or effective [1.3.4].

  • Oral vs. Topical: The proven benefits of blueberries for eyes are tied to oral consumption (eating them or taking supplements), not direct application [1.2.4, 1.3.3].

  • Stick to Proven Treatments: For dry eyes or irritation, use only FDA-approved artificial tears or products recommended by an eye doctor [1.8.4].

In This Article

The Power of Blueberries for Vision Health

The humble blueberry, and its European cousin the bilberry, have long been praised as superfoods for eye health [1.2.4]. This reputation is primarily due to their high concentration of powerful antioxidants called anthocyanins [1.2.5]. These pigments give berries their deep blue and purple colors and are the focus of scientific research for their potential health benefits. Studies suggest that dietary intake of blueberries and their extracts can contribute to overall eye wellness in several ways [1.2.6]. The antioxidants, particularly anthocyanins, help defend the delicate tissues of the eye against oxidative stress, a key factor in age-related eye conditions [1.2.4]. Research has linked regular blueberry consumption to a reduced risk of age-related macular degeneration (AMD) and cataracts [1.2.3, 1.4.4]. Furthermore, some studies indicate that the compounds in blueberries can improve blood flow to the retina and may help alleviate eye fatigue and strain, especially in the context of prolonged screen use [1.2.3, 1.4.7]. A pilot study also showed that oral supplements containing bilberry extract and fish oil improved signs and symptoms of severe dry eye [1.7.5]. These benefits, however, are associated with consuming the berries or their extracts, allowing the body to process and deliver these compounds to the eyes through the bloodstream [1.4.3].

What Are Blueberry Eye Drops Supposed to Do?

Given the known benefits of dietary blueberries, a market has emerged for "blueberry eye drops." These products claim to deliver the antioxidant power of blueberries directly to the surface of the eye. Purported benefits often mirror those of oral supplements, including relief from dryness, redness, blurred vision, and general eye fatigue [1.5.1]. The logic seems straightforward: if blueberry compounds are good for the eyes, applying them directly should be even better. These products are often marketed as "natural" solutions for a variety of common eye complaints, from digital eye strain to discomfort from environmental irritants [1.5.1]. However, the leap from the benefits of oral consumption to topical application is a significant one that lacks rigorous scientific validation and overlooks critical safety considerations.

The Critical Lack of Evidence and FDA Warnings

There is a profound lack of credible, peer-reviewed scientific studies validating the effectiveness or safety of applying blueberry extract directly to the eyes via drops. The vast majority of research, including studies on bilberry for dry eye and anthocyanins for retinal health, involves oral supplements [1.3.3, 1.3.5]. Most importantly, blueberry eye drops are not approved by the U.S. Food and Drug Administration (FDA) [1.5.3, 1.5.5]. The FDA has issued numerous warnings against using unapproved eye drops due to the risk of contamination and serious infection [1.6.1, 1.6.6]. Products used in the eyes must be manufactured in sterile conditions to prevent bacterial contamination, which can lead to infections, vision loss, or even blindness [1.6.3, 1.6.5]. The FDA explicitly states that no OTC treatments for serious conditions like glaucoma or cataracts are approved, and consumers should be wary of any product making such claims [1.5.5]. Some health authorities have issued direct warnings about specific "natural" eye drop products, including those marketed as blueberry-based, for being unregistered and potentially dangerous [1.5.2, 1.5.3].

Comparison Table: Oral Supplements vs. Unregulated Drops

Feature Oral Blueberry/Bilberry Supplements Unregulated Blueberry Eye Drops
Scientific Evidence Supported by studies for reducing AMD risk, relieving eye fatigue, and potentially helping dry eye symptoms when consumed [1.2.3, 1.4.4, 1.7.2]. No credible scientific evidence for topical application in humans. Claims are unsubstantiated [1.3.1, 1.3.4].
Regulatory Status Regulated as dietary supplements. Quality can vary. Not approved by the FDA. Often sold illegally with unverified claims [1.5.3, 1.5.5].
Safety Generally considered safe when taken at appropriate doses. Some minor side effects possible [1.3.3]. High risk of bacterial contamination, infection, and serious eye damage. The FDA warns against use [1.6.1, 1.6.3].
Mechanism Anthocyanins are absorbed through digestion and delivered to eye tissues via the bloodstream [1.4.3]. Claims to work via direct topical absorption, a mechanism not proven to be effective or safe for these compounds [1.5.3].
Recommendation Can be part of a holistic approach to eye health, alongside a balanced diet. Consult a doctor first [1.8.4]. Strongly advised against. Poses significant health risks. Use only FDA-approved eye drops [1.6.1, 1.5.5].

Conclusion: Stick to Science and Safety

While eating blueberries is a delicious and evidence-supported way to promote long-term eye health, the same cannot be said for blueberry eye drops. The benefits associated with these berries come from systemic absorption through diet, not topical application. The use of unregulated, non-FDA-approved eye drops carries a significant and severe risk of eye infections that could lead to permanent vision loss [1.6.3]. The claims made by these products are not backed by scientific research, and their manufacturing standards are unverified [1.5.2]. For eye discomfort such as dryness or strain, it is crucial to use only FDA-approved artificial tears or medications prescribed by an eye care professional [1.8.4]. Protecting your vision means relying on proven, regulated treatments and not falling for the hype of potentially dangerous products.

For more information on eye drop safety, you can visit the FDA's consumer information page: https://www.fda.gov/drugs/buying-using-medicine-safely/what-you-should-know-about-eye-drops [1.5.5].

Frequently Asked Questions

No, blueberry eye drops are not considered safe because they are not approved by the FDA. Using unapproved eye drops carries a significant risk of bacterial contamination, which can cause serious eye infections and potential vision loss [1.5.5, 1.6.1].

There is no credible scientific evidence from rigorous clinical studies to support the effectiveness of applying blueberry extract directly to the eyes. The research on blueberries and eye health is based on oral consumption through diet or supplements [1.3.1, 1.3.4].

Dietary consumption of blueberries is linked to several benefits, including supporting healthy blood vessels in the eyes, reducing the risk of age-related macular degeneration (AMD), and potentially lowering the risk of cataracts, largely due to their high antioxidant (anthocyanin) content [1.2.6, 1.2.3, 1.4.4].

Some studies involving oral supplements of bilberry (a close relative of blueberry) combined with other ingredients like fish oil have shown preliminary improvements in the signs and symptoms of dry eye [1.7.2, 1.7.5]. There is no evidence that topical drops are effective for this.

Unregulated eye drops are dangerous because they are not manufactured under the sterile conditions required by the FDA. This can lead to contamination with harmful bacteria, posing a risk of infections that could lead to blindness or more severe, life-threatening conditions [1.6.3, 1.6.5].

For eye strain and dryness, you should use FDA-approved over-the-counter artificial tears, practice the 20-20-20 rule for screen time, and ensure proper lighting. If symptoms persist, consult an eye care professional for diagnosis and treatment [1.8.3, 1.8.4].

When you eat blueberries, anthocyanins are absorbed into your bloodstream and can cross the blood-retinal barrier. They act as powerful antioxidants, protecting delicate eye cells from damage, improving blood flow, and supporting functions like rhodopsin regeneration, which is important for vision [1.4.3, 1.2.4, 1.4.5].

References

  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
  6. 6
  7. 7
  8. 8
  9. 9
  10. 10
  11. 11
  12. 12
  13. 13
  14. 14
  15. 15
  16. 16
  17. 17
  18. 18
  19. 19
  20. 20
  21. 21
  22. 22
  23. 23
  24. 24
  25. 25
  26. 26

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.