What is Marvelon?
Marvelon is a type of birth control known as a combined oral contraceptive pill [1.2.2]. It contains two synthetic female hormones: an estrogen (ethinylestradiol) and a progestin (desogestrel) [1.2.5, 1.4.6]. As a low-dose contraceptive, it provides a reliable and reversible method for preventing pregnancy when taken correctly [1.2.2]. Marvelon is a monophasic pill, meaning each of the 21 active pills in a pack contains a consistent dose of these hormones [1.6.7]. After 21 days of taking the pill, there is typically a 7-day break during which a withdrawal bleed, similar to a period, occurs [1.2.1].
How Marvelon Works
The primary function of Marvelon is to prevent pregnancy, which it accomplishes through a three-pronged mechanism of action [1.2.1, 1.4.5]:
- Inhibition of Ovulation: The hormones in Marvelon suppress the release of gonadotropins, which are hormones that normally trigger the ovaries to release an egg each month. By preventing ovulation, there is no egg available for sperm to fertilize [1.4.1, 1.4.2].
- Thickening of Cervical Mucus: The pill causes the mucus in the cervix to become thicker. This makes it more difficult for sperm to pass through the cervix and enter the uterus to reach an egg [1.2.2, 1.4.5].
- Alteration of the Uterine Lining: The hormones also change the lining of the uterus (the endometrium), making it thinner and less suitable for a fertilized egg to implant and grow [1.2.1, 1.4.4].
When used perfectly, meaning taken every day without missing a dose, combined pills are over 99% effective [1.7.1]. However, typical use effectiveness is around 93%, accounting for human error like forgetting pills [1.7.3].
Contraceptive Benefits of Marvelon
The most direct benefit of Marvelon is its high reliability as a reversible contraceptive method [1.2.2]. If started on the first day of a menstrual cycle, it provides immediate protection against pregnancy [1.2.5]. Unlike some other contraceptive methods, it does not interrupt sexual activity [1.2.5]. Furthermore, fertility typically returns to normal shortly after discontinuing the pill [1.2.4].
Non-Contraceptive Health Benefits
Beyond pregnancy prevention, Marvelon and other combined oral contraceptives offer a wide array of secondary health benefits that can significantly improve quality of life for many users.
Menstrual Cycle Regulation and Symptom Relief
- Regularity and Lighter Periods: Marvelon can make menstrual cycles more regular, predictable, and lighter [1.2.2, 1.2.5]. This can lead to a lower risk of iron-deficiency anemia [1.5.6].
- Reduced Period Pain: Many users experience less severe menstrual cramps (dysmenorrhea), and in some cases, period pain may disappear completely [1.2.2, 1.5.6]. This is because the pill reduces the production of prostaglandins, chemicals that cause uterine contractions and cramping [1.3.1].
- Alleviation of PMS/PMDD: Symptoms of Premenstrual Syndrome (PMS) and the more severe Premenstrual Dysphoric Disorder (PMDD) can be improved. By preventing ovulation, the pill stabilizes the hormonal fluctuations that can trigger these symptoms [1.2.2, 1.3.1].
Improvements in Skin and Hair
Marvelon is often noted for its positive effects on the skin [1.2.4]. The hormones in the pill can reduce the levels of androgens (male hormones) in the body [1.2.5, 1.3.2]. This anti-androgenic effect can lead to a significant improvement in hormonal acne [1.2.5]. It is a good option for those who have experienced acne problems with other types of pills [1.2.4].
Management of Gynecological Disorders
Combined pills like Marvelon are frequently prescribed to manage symptoms of various gynecological conditions:
- Polycystic Ovary Syndrome (PCOS): By regulating hormones, Marvelon can help manage symptoms of PCOS, such as irregular periods and acne [1.2.4, 1.3.2].
- Endometriosis: The pill can reduce the pelvic pain associated with endometriosis by limiting the growth of endometrial tissue outside the uterus [1.3.1, 1.3.2].
- Ovarian Cysts: Use of combined oral contraceptives can reduce the formation of new functional ovarian cysts [1.3.2, 1.5.6].
Reduced Cancer Risk
Long-term use of combined oral contraceptives has been shown to offer significant protection against certain types of cancer:
- Ovarian and Endometrial Cancer: Studies have demonstrated that using the pill lowers the risk of developing both ovarian and endometrial (womb) cancer [1.2.5, 1.3.2, 1.7.5]. This protective effect can persist for many years even after stopping the medication [1.7.5].
- Colon Cancer: Evidence also suggests a reduced risk of colon cancer among users of combined oral contraceptives [1.2.4, 1.3.2].
Comparison with Other Contraceptive Pills
Marvelon is a third-generation combined pill, primarily due to its progestin, desogestrel. How it compares to other pills often comes down to the type and dose of its hormones.
Feature | Marvelon (Monophasic) | Mercilon (Monophasic) | Yasmin (Monophasic) | Loestrin (Monophasic) |
---|---|---|---|---|
Estrogen (EE) | 30 mcg [1.2.5] | 20 mcg [1.6.5] | 30 mcg | 20 mcg |
Progestin | Desogestrel (150 mcg) [1.2.5] | Desogestrel (150 mcg) [1.6.5] | Drospirenone | Norethindrone Acetate |
Key Characteristics | Good for acne control; standard estrogen dose [1.2.4]. | Lower estrogen dose may mean fewer side effects for some [1.6.5]. | Anti-androgenic; can help with water retention. | Different progestin family (first-generation). |
VTE Risk | Slightly higher risk of blood clots (VTE) compared to second-generation pills [1.2.2]. | Slightly higher VTE risk, similar to Marvelon [1.6.4]. | Higher VTE risk compared to second-generation pills. | Generally lower VTE risk than third-generation pills. |
Note: This table is for informational purposes. The best pill choice is highly individual and must be determined with a healthcare provider. The main difference between Marvelon and Mercilon is the estrogen dose; Mercilon contains a lower dose (20mcg vs. 30mcg), which may be preferable for those sensitive to estrogen [1.6.5]. Gedarel is another brand that is very similar to Marvelon, containing the same active ingredients in the same amounts [1.6.6].
Potential Risks and Important Considerations
Despite its benefits, Marvelon is not suitable for everyone and carries potential risks. The most serious risk associated with combined hormonal contraceptives is an increased risk of blood clots, which can lead to deep vein thrombosis (DVT), pulmonary embolism, stroke, or heart attack [1.2.2]. This risk is small but higher for users of pills containing desogestrel, like Marvelon, compared to some other pills [1.2.2]. The risk is also elevated in women who smoke, are over 35, are very overweight, or have a personal or family history of blood clots [1.2.2, 1.5.1].
Other side effects can include headaches, nausea, breast tenderness, mood changes, and weight gain [1.5.6, 1.5.7]. Some women may experience breakthrough bleeding or spotting, especially during the first few months of use [1.5.1].
Conclusion
Marvelon is a highly effective contraceptive pill that offers a wealth of non-contraceptive benefits. Its ability to regulate menstrual cycles, reduce period pain, improve acne, and lower the risk of several serious cancers makes it a valuable medication for many women [1.2.2, 1.2.4, 1.2.5]. However, the decision to take Marvelon must be made in consultation with a healthcare provider who can assess individual health status, discuss the potential risks, particularly concerning blood clots, and determine if it is the most appropriate choice [1.2.2].
For more information, you can consult the Patient Information Leaflet on medicines.org.uk.