Ferrodan is a brand name for iron supplements, and as search results indicate, the specific ingredients can vary depending on the product's formulation and the manufacturer. The primary purpose of all Ferrodan products is to treat or prevent iron deficiency anemia. However, the specific iron compound and excipients differ, affecting tolerance, absorption, and overall side effect profiles.
Ferrodan Oral Solution Ingredients
For the liquid syrup formulation, such as the one described by Medsafe and Odan, the active and inactive ingredients are clearly defined. This is a commonly prescribed form, particularly for children and individuals who have difficulty swallowing tablets.
Active Ingredient
- Ferrous Sulfate Heptahydrate: The active medicinal component in the oral solution. In one formulation, each milliliter contains 30 mg of ferrous sulfate heptahydrate, which is equivalent to 6 mg of elemental iron. Elemental iron is the amount of iron that is actually available for the body to absorb and use.
Inactive Ingredients
These are added to provide flavor, act as a preservative, or to improve the texture and stability of the product. For the oral solution, these include:
- Sweeteners: Sucrose and sorbitol, to improve the taste, are significant ingredients for patients with diabetes or hereditary fructose intolerance.
- Flavorings: Lemon, pineapple, and strawberry flavours give the syrup a fruity taste, making it more palatable.
- Preservatives: Sodium benzoate and sodium bisulfite are used to prevent microbial growth and maintain product shelf life.
- Other Components: Glycerine, citric acid, and purified water complete the liquid formulation.
Ferrodan Fe2+ Tablet Ingredients
Another version of Ferrodan, notably the Ferrodan Fe2+ tablets from Vitabalans, uses a different type of iron compound and includes vitamin C. This chelated iron form is often promoted for better tolerability.
Active Ingredients
- Ferrous(II)bisglycinate: This is a chelated form of iron, meaning the iron is bound to two molecules of the amino acid glycine. This chelation is believed to enhance absorption and reduce common gastrointestinal side effects associated with iron supplements.
- L-ascorbic acid: Also known as Vitamin C, this is included in the formulation to enhance the absorption of iron from the digestive tract.
Inactive Ingredients
To form the film-coated tablets, a variety of excipients are used:
- Bulking Agents: Cellulose and hydroxypropyl methyl cellulose are used to add bulk and help form the tablet.
- Anti-caking Agent: Silicon dioxide prevents the ingredients from clumping together.
- Glazing Agents: Polyvinyl alcohol, calcium carbonate, polyethylene glycol, and magnesium salts of fatty acids create the smooth outer coating.
- Colours: Iron oxides are added for tablet coloration.
Comparison of Ferrodan Formulations
The table below provides a quick overview of the key differences between the oral solution and tablet formulations of Ferrodan based on available product information.
| Feature | Ferrodan Oral Solution | Ferrodan Fe2+ Tablets |
|---|---|---|
| Active Iron Compound | Ferrous Sulfate Heptahydrate | Ferrous(II)bisglycinate |
| Absorption Enhancer | None specified; may be taken with vitamin C | L-ascorbic acid (Vitamin C) is included |
| Tolerability | Can cause gastrointestinal irritation, nausea, and constipation | Chelate form is often marketed as more easily tolerated with fewer side effects |
| Form and Appearance | Syrupy liquid with fruit flavours; colour can vary | Film-coated tablets |
| Sweeteners | Sucrose and sorbitol are included | Specific sweeteners not noted in Vitabalans product info, but film-coated |
| Allergens/Sensitivities | Contains sugars, benzoates, and sulfites | Contains cellulose and other coating components |
Understanding Elemental Iron
When comparing iron supplements, it is important to look at the amount of elemental iron, not just the total weight of the iron compound. As seen in the search results, the oral solution contains 6 mg of elemental iron per mL, while the Vitabalans tablets provide either 50 mg or 100 mg of elemental iron per tablet, depending on the dosage. This value represents the actual amount of iron the body can utilize. A physician will typically recommend a dosage based on your specific elemental iron needs.
Conclusion
In summary, the ingredients in Ferrodan vary depending on the specific product and formulation. The oral solution contains ferrous sulfate heptahydrate as its active ingredient, along with sweeteners and preservatives. In contrast, the Ferrodan Fe2+ tablets from some manufacturers use a more bioavailable ferrous(II)bisglycinate, and often include Vitamin C to aid absorption. For any iron deficiency, it is vital to consult a healthcare provider to determine the best course of action and the most appropriate supplement. Always read the specific product label and be aware of potential sensitivities to inactive ingredients like sugars or sulfites. For further technical details, the official datasheets for products are excellent resources, such as those provided by regulatory bodies like Medsafe.
