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What are the most common side effects of FLONASE?

4 min read

Clinical trials show that less than 2% of patients discontinue FLONASE due to adverse reactions, but mild, temporary side effects are common. This article explores what are the most common side effects of FLONASE, how to minimize them, and when to consult a doctor.

Quick Summary

FLONASE's most common side effects include nasal irritation, nosebleeds, and headaches, though they are often mild and temporary. Proper technique can minimize these effects, while serious issues like thrush or vision changes are rare but require attention.

Key Points

  • Common Effects Are Mild: Most FLONASE users experience mild and temporary side effects, such as headaches, nasal irritation, and sore throat, which are often related to local nasal application.

  • Proper Technique is Key: Correctly aiming the spray towards the outer nasal wall can significantly reduce the risk of nosebleeds and irritation.

  • Long-Term Use Warrants Caution: Extended use, especially in children, increases the risk of rare but serious side effects like thrush, cataracts, or slowed growth, so long-term users should be monitored.

  • Stay Hydrated and Rinse: Drinking plenty of water and rinsing your mouth after each use can help mitigate side effects like headaches, sore throat, and unpleasant taste.

  • Know When to Call a Doctor: Seek medical advice for severe or persistent side effects, any signs of infection, or vision changes.

In This Article

FLONASE, an over-the-counter nasal corticosteroid spray, is a highly effective treatment for seasonal and year-round allergies. Its active ingredient, fluticasone, works by reducing inflammation in the nasal passages to relieve symptoms like sneezing, itchy eyes, and nasal congestion. While many people use it daily without issues, some individuals may experience side effects. Understanding these potential reactions and how to manage them is key to a positive treatment experience.

Common Side Effects of FLONASE

For many users, side effects are mild and manageable. The most frequently reported issues are related to the local application of the nasal spray. These include:

  • Headache: This is one of the most common side effects reported by FLONASE users, though it is more prevalent at higher dosages.
  • Nasal Irritation or Burning: The sensation of dryness, burning, or stinging in the nose is a common local effect, potentially caused by the propellant or direct contact with nasal tissue.
  • Nosebleeds (Epistaxis): Nosebleeds can occur, especially with long-term use, as the medication can thin the delicate blood vessels in the nasal passages.
  • Sore Throat and Cough: If the medication drips down the back of the throat, it can cause a sore throat, dry throat, or coughing.
  • Nausea and Vomiting: Some users may experience an upset stomach, often caused by the medication draining into the throat and being swallowed.
  • Unpleasant Taste or Smell: A change or loss in the sense of taste and/or smell is also possible.

How to Minimize Common FLONASE Side Effects

Proper administration can significantly reduce the risk and severity of these common side effects. Following these steps can help:

  1. Use the correct spraying technique: When spraying, aim the nozzle toward the outer wall of the nostril, away from the nasal septum (the cartilage dividing the nose). This helps prevent damage and reduce the risk of nosebleeds.
  2. Rinse your mouth: To prevent sore throat and an unpleasant taste, rinse your mouth with water or gargle after using the spray.
  3. Use a saline spray: Using a saline nasal spray or rinse a few minutes before FLONASE can help moisten the nasal passages and reduce irritation and nosebleeds.
  4. Stay hydrated: Drinking plenty of fluids can help with headaches and general discomfort.
  5. Use a humidifier: In dry climates or during winter, a humidifier can help prevent nasal dryness.

Less Common and Serious Side Effects

While rare, it is important to be aware of potentially more serious side effects. If you experience any of the following, contact your healthcare provider immediately:

  • Oral or Nasal Thrush: A fungal infection (Candida) can develop in the nose or mouth, appearing as white patches.
  • Nasal Ulcers or Perforation: Open sores or damage to the nasal septum can occur. A persistent whistling sound when breathing can be a sign of a perforated septum.
  • Eye Problems: Long-term corticosteroid use may rarely lead to cataracts or glaucoma. Regular eye exams are recommended for long-term users, especially those with existing risk factors.
  • Slowed Growth in Children: Intranasal corticosteroids may cause a reduction in growth velocity in children. Pediatricians should monitor the growth of children using these medications long-term.
  • Allergic Reactions: Severe allergic reactions (anaphylaxis) are extremely rare but possible. Symptoms include rash, swelling of the face or tongue, and trouble breathing.

FLONASE vs. Other Nasal Sprays: Side Effect Comparison

Choosing between different nasal corticosteroids can be difficult, as many share similar side effect profiles. Here is a comparison of FLONASE (fluticasone) with another popular option, Nasacort (triamcinolone).

Side Effect FLONASE (Fluticasone Propionate/Furoate) Nasacort (Triamcinolone) Key Takeaway
Headache Common Common Both can cause headaches, but higher doses of Flonase may increase risk.
Nasal Irritation Common, though Flonase Sensimist may be less irritating than original Flonase. Common, but is alcohol-free which may be less drying for some. Formulation differences may impact irritation levels for individuals.
Nosebleeds Common, especially with long-term use. Common. Both carry a risk of nosebleeds, with proper technique being essential for both.
Sore Throat Common. Common. Caused by post-nasal drip for both; rinsing is a good preventative measure.
Oral/Nasal Thrush Rare, but possible with long-term use. Rare. Fungal infection risk is present for both; practice good hygiene.

Special Considerations for Long-Term FLONASE Use

Many individuals can use FLONASE on a daily basis for extended periods safely. However, prolonged use, especially at higher doses, can increase the risk of certain side effects. Concerns include nasal ulcers, a higher risk of infections due to immunosuppression, and hormonal changes (adrenal suppression), though the latter is primarily associated with high-dose or systemic steroid use. It is recommended for adults using FLONASE for more than six months, and children using it for more than two months per year, to consult a healthcare provider for monitoring.

For more detailed product information, refer to the MedlinePlus Drug Information on Fluticasone Nasal Spray.

Conclusion

FLONASE is an effective and generally well-tolerated treatment for allergy symptoms. The most common side effects—including headaches, nasal irritation, and nosebleeds—are often mild and can be managed with proper spray technique and hydration. While serious side effects are rare, it is important to be aware of them, especially with long-term use. By understanding the potential side effects and practicing careful usage, individuals can safely use FLONASE to manage their allergy symptoms and achieve relief. Always consult a healthcare provider with any persistent or concerning side effects.

Frequently Asked Questions

Yes, headaches are one of the most commonly reported side effects of FLONASE. In clinical studies, this was reported more frequently, especially with higher dosages.

To prevent nosebleeds, make sure to aim the spray nozzle toward the outer wall of your nostril, avoiding the nasal septum. Using a saline nasal spray beforehand and a humidifier can also help moisten nasal passages.

Many people can use FLONASE daily for extended periods. However, long-term use can increase the risk of certain side effects like thrush, nasal ulcers, and, rarely, eye issues. Long-term users should consult a doctor for monitoring.

Yes, intranasal corticosteroids like FLONASE can cause a reduction in growth velocity in children. Pediatricians should monitor the growth of any child on long-term treatment.

Anxiety is a rare and potentially unproven side effect. Some reports exist, but experts are unsure of the direct cause. If you experience nervousness, stop using the spray and contact your doctor.

Nasal thrush is a fungal infection caused by Candida that can appear as white patches in the nose or throat. In rare cases, FLONASE can cause this, and proper technique and hygiene can help prevent it.

FLONASE and Nasacort have very similar side effect profiles, including headaches, sore throat, and nasal irritation. Nasacort is alcohol-free, which may lead to less dryness for some people, but overall effectiveness and safety are comparable.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.