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What are the negative side effects of the pill?

5 min read

Surveys show that about 35% of women who have used birth control report experiencing at least one side effect [1.5.5]. Understanding what are the negative side effects of the pill can help you make an informed decision with your healthcare provider.

Quick Summary

Oral contraceptives can cause various side effects, ranging from temporary issues like nausea and breast tenderness to rare but serious risks including blood clots and an altered risk profile for certain cancers.

Key Points

  • Common Side Effects: Nausea, headaches, breast tenderness, and breakthrough bleeding are common, especially in the first 3 months [1.2.3, 1.2.4].

  • Serious Risks are Rare: The most serious risks, like blood clots, heart attack, and stroke, are rare but require immediate medical attention [1.3.1, 1.2.6].

  • Cancer Risk is Complex: The pill slightly increases the risk of breast and cervical cancer but decreases the risk of ovarian, endometrial, and colon cancer [1.3.4, 1.3.5].

  • Side Effects are Manageable: Many minor side effects can be managed at home and often disappear after 2-3 months [1.4.2, 1.7.3].

  • Pill Type Matters: Different hormone formulations (e.g., combination vs. progestin-only) have different side effect profiles and risks [1.6.2, 1.6.4].

  • Consult a Doctor: If side effects persist for more than three months or are severe, a doctor may recommend a different pill or method [1.7.4].

  • Know Warning Signs: Severe leg or chest pain, sudden severe headaches, or shortness of breath are warning signs that require emergency care [1.2.1, 1.2.4].

In This Article

Understanding the Side Effects of Oral Contraceptives

Oral contraceptive pills, commonly known as "the pill," are a widely used and highly effective method for preventing pregnancy [1.6.6]. They work by using hormones to regulate or stop ovulation. While millions use the pill safely, it's a medication that can cause a range of side effects [1.7.3, 1.8.1]. These effects stem from the body adjusting to the hormones, primarily estrogen and progestin, and can vary significantly from person to person [1.4.4, 1.2.2]. Most minor side effects tend to resolve within the first two to three months as your body acclimates [1.2.3, 1.7.3]. However, some can be more persistent or serious.

Common and Temporary Side Effects

When first starting the pill, it's not uncommon to experience mild side effects. These are often the body's initial reaction to hormonal changes and typically fade over time [1.2.4].

  • Nausea: A frequent complaint, especially when starting the pill [1.2.4]. Estrogen can irritate the stomach lining [1.4.5]. Taking the pill with food or at bedtime can help mitigate this [1.4.1, 1.4.6].
  • Headaches: Some individuals may experience new or worsening headaches [1.2.1]. These can be related to the hormonal fluctuations, similar to menstrual migraines [1.2.4].
  • Breast Tenderness: Hormonal shifts can cause breasts to feel sore or tender, a side effect that usually diminishes after a few cycles [1.2.1, 1.2.3].
  • Breakthrough Bleeding or Spotting: Irregular bleeding between periods is very common in the first few months of use, particularly with continuous-dosing or progestin-only pills [1.2.1, 1.2.5].
  • Mood Changes: Some users report experiencing mood swings, irritability, or other emotional changes [1.2.2, 1.2.5]. While the direct link to depression is still studied, it's a reported side effect [1.2.4].
  • Bloating and Water Retention: You might feel puffy or notice a slight weight change, which is typically temporary water retention, not fat gain [1.2.4].

Less Common Side Effects

Beyond the initial adjustment period, some less frequent side effects can occur. If these persist, consulting a doctor is recommended [1.7.3].

  • Decreased Libido: Hormonal changes can sometimes lower a person's interest in sex [1.2.2].
  • Changes in Vaginal Discharge: The pill can alter the amount or consistency of vaginal discharge [1.2.3].
  • Hair Loss: While uncommon, some may experience hair thinning, which may be more likely with certain types of progestins [1.2.3].
  • Eye and Contact Lens Issues: The pill can sometimes reduce tear production, leading to dry eyes and discomfort for contact lens wearers [1.2.3].

Serious but Rare Side Effects and Long-Term Risks

Though very rare, oral contraceptives are associated with serious health risks that require immediate medical attention. The risk is higher for individuals with certain pre-existing conditions, those over 35 who smoke, or those with a family history of specific disorders [1.2.2, 1.7.5].

Vascular Risks

The most significant serious risk is an increased chance of developing blood clots, which can lead to life-threatening conditions [1.2.1]. Estrogen-containing pills are primarily associated with this risk [1.2.2].

  • Blood Clots (Venous Thromboembolism): A blood clot in the leg (deep vein thrombosis) or lungs (pulmonary embolism) is a rare but serious side effect [1.3.1]. The risk is very small, affecting up to 1 in 1,000 users of combined hormonal contraception [1.2.6].
  • Heart Attack and Stroke: The risk is slightly elevated, especially for those with other cardiovascular risk factors like smoking, high blood pressure, or diabetes [1.3.1, 1.3.3]. Pills with higher estrogen doses carry a greater risk [1.3.5].
  • High Blood Pressure: Some users may experience an increase in blood pressure [1.2.1].

Cancer Risk Profile

The relationship between hormonal contraceptives and cancer is complex; the pill decreases the risk of some cancers while slightly increasing the risk of others.

  • Increased Risk: Long-term use of the pill is associated with a slightly higher risk of breast cancer and cervical cancer [1.3.5, 1.8.3]. The risk for breast cancer appears to return to normal about 10 years after stopping the pill [1.3.5]. The cervical cancer risk is primarily a concern for those with HPV and also declines after discontinuing the pill [1.3.5].
  • Decreased Risk: Conversely, using the pill lowers the risk of ovarian, endometrial, and colorectal cancers [1.3.4, 1.3.5]. This protective effect can last for many years after stopping the medication [1.3.5].

Comparison of Pill Types and Side Effects

Not all birth control pills are the same. They vary by hormone type and dosage, which can influence side effects [1.6.1].

Pill Type Hormone Content Common Associated Side Effects/Notes
Combination Pills Estrogen and Progestin Most common type. Higher estrogen doses may increase risks of headache and blood clots. Can be monophasic (same dose daily) or multiphasic (varied dose) [1.2.2, 1.6.1].
Progestin-Only Pills (Minipill) Progestin only Good option for those who cannot take estrogen due to health risks (e.g., smokers over 35, history of blood clots) [1.6.4, 1.6.6]. Irregular bleeding is a more common side effect [1.2.5].
Low-Dose Estrogen Pills Lower dose of estrogen May be preferred by those sensitive to hormones, but can cause more breakthrough bleeding [1.6.1].
Pills with Drospirenone A specific progestin Has diuretic properties that may help with bloating, but may have a higher blood clot risk compared to other progestins [1.6.2].
Pills with Levonorgestrel A specific progestin Associated with the lowest risk of blood clots among combination pills [1.3.1, 1.6.2].

Managing Side Effects and When to See a Doctor

Many common side effects can be managed with simple home remedies. For example, taking the pill with food can ease nausea, and over-the-counter pain relievers can help with headaches [1.2.3, 1.4.1]. If side effects are severe or persist beyond three months, you should consult your healthcare provider [1.7.4]. They might suggest switching to a different pill formulation or another birth control method entirely [1.7.2].

It is crucial to seek immediate medical attention if you experience any signs of a serious problem, such as:

  • Severe abdominal or chest pain [1.2.1]
  • Severe headaches, especially with vision changes [1.2.4]
  • Swelling, pain, or discoloration in a leg [1.2.1]
  • Shortness of breath [1.7.4]
  • Yellowing of the skin or eyes (jaundice) [1.2.1]

Conclusion

While the birth control pill is a safe and effective contraceptive for most people, it comes with a range of potential negative side effects. The majority are mild and temporary, but there are also rare and serious risks to consider. The non-contraceptive benefits, such as a reduced risk of certain cancers and management of menstrual symptoms, are also an important part of the conversation [1.9.4, 1.9.5]. A thorough discussion with a healthcare provider about your personal and family medical history is essential to determine if the pill is the right choice for you and to find the formulation that best suits your body.


For more information from an authoritative source, you can visit the Mayo Clinic's guide on combination birth control pills.

Frequently Asked Questions

Most common and mild side effects, such as nausea, headaches, and breakthrough bleeding, typically improve or disappear within the first 2 to 3 months as your body adjusts to the hormones [1.7.3, 1.2.4].

While some people report feeling bloated, which can be mistaken for weight gain, most studies have not found a direct link between modern birth control pills and significant fat gain [1.2.4]. The feeling of puffiness is often due to temporary water retention [1.2.4].

The most serious, though rare, side effects include an increased risk of blood clots (which can lead to a pulmonary embolism or stroke), heart attack, and a slightly elevated risk of breast and cervical cancer [1.3.1, 1.3.5].

Progestin-only pills do not contain estrogen and are generally not associated with an increased risk of blood clots, making them a safer option for individuals with certain health risks, like smokers over 35 [1.3.1, 1.6.6]. However, they may be more likely to cause irregular bleeding [1.2.5].

You should see a doctor if side effects persist for more than 3 months, are severe, or if you experience any warning signs of a serious condition like severe leg pain, chest pain, sudden severe headaches, or vision changes [1.7.4, 1.2.1].

Some individuals report mood swings, irritability, or new or worsening depression while on the pill [1.2.2, 1.2.4]. If you experience significant mood changes, it's important to discuss this with your healthcare provider [1.4.5].

Yes. If side effects are bothering you and don't improve after a few months, your doctor may suggest switching to a different brand with a different hormone dose or type, or trying another birth control method altogether [1.7.3].

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.