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What do benzos feel like? Understanding the effects of benzodiazepines

5 min read

In 2013, benzodiazepine prescriptions in the US peaked at 135 million, yet many people still wonder, what do benzos feel like? This class of drugs, used for anxiety and insomnia, can produce distinct feelings of calm and relaxation, but also carries significant risks related to dependence and overdose.

Quick Summary

Benzodiazepines produce feelings of calm and sedation by affecting brain chemicals like GABA. The experience varies by dose and individual, ranging from therapeutic relief to euphoric detachment with risks of dependence and adverse side effects.

Key Points

  • Calmness and Relaxation: The primary effect of benzos is a slowing of the central nervous system, leading to feelings of peace, tranquility, and reduced anxiety.

  • Dose-Dependent Effects: At low, therapeutic doses, the effects are controlled and focused on symptom relief, while high recreational doses can lead to euphoria, detachment, and impaired coordination.

  • Risk of Dependence and Withdrawal: Long-term or high-dose use can cause physical dependence, and abrupt cessation can lead to severe and potentially dangerous withdrawal symptoms, including seizures.

  • Impaired Cognition: Side effects often include memory loss (anterograde amnesia), confusion, and difficulty concentrating, which can be more pronounced in older adults.

  • Danger of Combination: Combining benzodiazepines with other CNS depressants like alcohol or opioids drastically increases the risk of fatal overdose due to severe respiratory depression.

  • Individual Variation: The effects and side effects of benzos vary widely depending on the specific drug, dosage, and the individual's metabolism, tolerance, and underlying health.

In This Article

The Science Behind the Feeling

Benzodiazepines, often called "benzos," are central nervous system (CNS) depressants that work by enhancing the effects of a neurotransmitter called gamma-aminobutyric acid, or GABA. GABA is the primary inhibitory neurotransmitter in the brain, meaning it reduces the activity of nerve cells. By binding to and modulating GABA-A receptors, benzos increase the inhibitory signals, which in turn slows down the communication between neurons.

This widespread slowing of neural activity is the root cause of the effects that users feel. Depending on the specific benzodiazepine and the dose, this can translate into a reduction of anxiety, muscle relaxation, sedation, and a feeling of calm. Different benzos also vary in their half-life and affinity for different types of GABA-A receptors, which accounts for the differences in their onset and duration of action. For example, a benzo designed for sleep (like triazolam) might have a quicker onset and shorter duration than one for anxiety (like clonazepam), which provides a longer-lasting effect.

The Therapeutic Experience: Calm and Controlled

For individuals with a medical prescription, the experience of taking a benzodiazepine at a therapeutic dose is typically one of relief from overwhelming symptoms. For those with severe anxiety or panic disorders, the medication can feel like a sudden return to normalcy. Racing thoughts slow down, and the physical symptoms of anxiety, such as a rapid heart rate and muscle tension, subside. This can allow a person to feel centered and in control during a panic attack or to sleep soundly through the night when suffering from insomnia.

While the primary therapeutic benefit is a sense of calm, many prescribed users also experience side effects, particularly at the beginning of treatment. These can include drowsiness, dizziness, and impaired coordination. For many, these initial side effects fade as their body develops a degree of tolerance. The feeling is often described as serene, peaceful, and tranquil, allowing the individual to cope with daily life without being paralyzed by their condition.

The Risks of Chasing a "Benzo High"

When misused or taken in higher-than-prescribed doses, the experience changes significantly and becomes far more dangerous. Recreational users may describe a sense of euphoria or a high, but this is a complex and risky sensation.

Euphoria vs. Sedation

At higher doses, the sedative effects of benzos are more pronounced and can lead to a sense of euphoric detachment from reality. This can be particularly appealing to individuals who use other stimulants, as benzos can help with the "come down". However, this euphoria is often followed by profound drowsiness, confusion, and impaired judgment, similar to alcohol intoxication. This is because both substances enhance GABA activity in the brain.

Detachment and Blackouts

A particularly dangerous effect of high-dose benzo use is anterograde amnesia—the inability to form new memories after taking the drug. This can lead to "blackouts," where an individual has no recollection of their actions for a period of time. During this state, people can engage in risky behaviors, and their inhibitions are severely lowered. In extreme cases, benzos have been implicated in drug-facilitated assaults due to this amnesic effect.

Factors Influencing the Benzodiazepine Experience

Several factors can alter how a benzodiazepine feels, including the specific drug, dosage, and the user's metabolism and tolerance.

Comparison of Benzodiazepine Effects

Feature Alprazolam (Xanax) Diazepam (Valium)
Primary Use Anxiety disorders, panic disorder Anxiety, alcohol withdrawal, muscle spasms, seizures
Onset of Action Faster (20-40 minutes) Rapid (15-40 minutes)
Duration of Effects Shorter (5-8 hours) Longer (4-6 hours active, but metabolites last for days)
Half-Life Intermediate (11-20 hours) Long (20-100 hours due to active metabolites)
Potency Higher potency on a milligram basis Lower potency than Xanax
Dependence Risk Higher risk for dependence due to short half-life Also habit-forming, but long half-life may make withdrawal slightly less severe initially

The Unpleasant Realities: Side Effects and Withdrawal

While the initial feelings of a benzo can be pleasant or offer relief, long-term use is associated with a range of challenging and sometimes dangerous effects.

Common Side Effects

  • Drowsiness, fatigue, and lethargy
  • Dizziness and impaired motor coordination (ataxia)
  • Mental confusion and memory problems
  • Slurred speech
  • Nausea or stomach cramps
  • Headaches
  • Changes in personality or irritability

The Withdrawal Experience

When a person becomes physically dependent on benzos and stops taking them abruptly, they will experience withdrawal. This is often described as the opposite of the drug's initial effects and can be intensely uncomfortable and, in some cases, life-threatening. The brain has adapted to the drug's presence, and its sudden absence can cause a surge of neural activity.

Symptoms can range from weeks to over a year and include:

  • Rebound anxiety: An intense return of anxiety, often worse than the original condition.
  • Physical symptoms: Headaches, muscle aches, tremors, and twitching.
  • Sleep disturbances: Insomnia and bizarre dreams.
  • Perceptual changes: Hypersensitivity to light, sound, smell, and touch.
  • Severe symptoms: In rare but serious cases, withdrawal can cause hallucinations, psychosis, or seizures, especially after prolonged use.

Conclusion: The Double-Edged Sword

For those who wonder what do benzos feel like, the answer is complex and depends heavily on the context of use. At therapeutic doses, they provide genuine relief from severe anxiety, panic, and insomnia, offering a feeling of calm and stability. However, this comes with the potential for side effects, including cognitive impairment and drowsiness. The risks multiply significantly with recreational use or long-term dependency, which can lead to euphoria, memory blackouts, and, ultimately, a harrowing withdrawal process. Given the risks of dependence and the dangers of combining benzos with other CNS depressants like alcohol, these medications should only be used under strict medical supervision and for short-term purposes. A robust understanding of both the desired and adverse effects is crucial for anyone considering or currently using these powerful drugs. For an in-depth look at benzodiazepine pharmacology, visit the National Institutes of Health (NIH) website.

Potential for Dependence and Risk of Overdose

The risk of developing a tolerance and dependence on benzodiazepines is a significant factor in how they are experienced over time. For many, tolerance develops in just a few weeks, meaning they need higher doses to achieve the same effect. This can lead to a cycle of dependence where the primary motivation for taking the drug shifts from seeking a specific effect to simply staving off unpleasant withdrawal symptoms. The feeling of needing the drug to function normally becomes a central part of the experience, altering mood, memory, and overall well-being. In the most serious cases, the search for a stronger high or the need to counteract tolerance can lead to accidental overdose, especially when combined with other CNS depressants.

The Lingering Effects: Beyond the High

For some, the experience with benzodiazepines does not end with withdrawal. Prolonged use has been linked to potential long-term cognitive and emotional challenges, sometimes referred to as Benzodiazepine-Induced Neurological Dysfunction (BIND). This can involve lingering anxiety, memory problems, and a reduced ability to cope with stress, long after the drug has left the system. The subjective experience of these lingering effects can be profoundly different from the initial feelings of calm, serving as a stark reminder of the drug's long-lasting impact on brain chemistry and function. This underscores the importance of cautious, short-term use under professional guidance.

Frequently Asked Questions

The onset of effects varies, but generally, benzodiazepines start working quickly. Short-acting versions like alprazolam can take effect within 20 to 40 minutes, while others may take slightly longer, but most are felt within an hour.

No, while they share a similar mechanism of action, the subjective feeling can differ based on potency, onset time, and duration of action. For example, a potent, fast-acting benzo might feel different than a less potent, long-acting one.

At higher, recreational doses, benzodiazepines can induce a sense of euphoria or detachment, but this is accompanied by increased risks, such as blackouts and impaired judgment.

Early signs of withdrawal, particularly after prolonged use, include rebound anxiety, insomnia, headaches, muscle cramps, and tremors. The intensity and exact symptoms can vary depending on the specific drug and how long it was used.

Mixing benzos with alcohol is extremely dangerous. Both are CNS depressants, and their combined effect can lead to extreme drowsiness, respiratory depression, coma, and death.

Yes. Tolerance can develop in a matter of weeks for many individuals, requiring higher doses to achieve the same effect. This is a significant factor in dependence and misuse.

In therapeutic use, benzos offer a controlled sense of calm and relief from anxiety at a prescribed dose. Recreational abuse involves higher doses to achieve a euphoric or detached feeling, which drastically increases the risk of side effects like blackouts, poor coordination, and dangerous outcomes.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.