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What Does Dimethicone Do to Your Body? A Pharmacological Review

4 min read

Dimethicone is an FDA-approved skin protectant, used in concentrations of 1-30% in over-the-counter products [1.9.1]. But beyond its regulatory status, what does dimethicone do to your body? This silicone-based polymer serves as a multi-functional ingredient in both skincare and internal medicine.

Quick Summary

Dimethicone is a silicone-based polymer that primarily forms a protective, breathable barrier on the skin to lock in moisture and protect from irritants. It's also used internally to relieve gas.

Key Points

  • Skin Protection: Dimethicone forms a breathable, protective barrier on the skin that locks in moisture and shields against irritants [1.6.2, 1.4.4].

  • Gas Relief: Internally, dimethicone (as simethicone) works by breaking down gas bubbles in the stomach and intestines, relieving bloating [1.3.2].

  • Safety Profile: The FDA approves dimethicone as a skin protectant, and it's widely considered safe, non-toxic, and non-carcinogenic for human use [1.9.1, 1.4.1].

  • Non-Comedogenic: Contrary to some beliefs, dimethicone is non-comedogenic, meaning it does not clog pores and is suitable for most skin types, including acne-prone skin [1.10.1, 1.10.2].

  • Emollient Properties: It acts as an emollient, smoothing the skin's surface by filling in fine lines, which gives cosmetic products a silky feel [1.4.1].

  • Scar Treatment: High-concentration dimethicone is used in silicone gels and sheets to help manage and reduce the appearance of scars [1.4.2, 1.6.2].

  • Environmental Concerns: Although safe for humans, dimethicone is not biodegradable and its accumulation in waterways is an environmental concern [1.11.1, 1.11.4].

In This Article

Understanding Dimethicone: A Dual-Action Polymer

Dimethicone is a synthetic silicone-based polymer, also known as polydimethylsiloxane (PDMS) [1.3.2]. Its large molecular weight means it primarily sits on the surface of the skin rather than being absorbed, a key factor in its safety profile [1.3.4, 1.4.2]. In pharmacology, dimethicone has two primary, yet distinct, applications: as a topical skin protectant and as an internal antiflatulent (often as its activated form, simethicone).

As a skin protectant, the U.S. Food and Drug Administration (FDA) has approved its use in over-the-counter (OTC) products at concentrations between 1% and 30% [1.9.1]. It is widely regarded as a safe and effective ingredient by regulatory bodies like the FDA and the Cosmetic Ingredient Review (CIR) Expert Panel [1.9.2, 1.9.4].

How Dimethicone Works on the Skin

When applied topically, dimethicone leverages its unique molecular structure to provide several benefits for the skin [1.4.2, 1.6.4]:

  • Forms a Protective Barrier: It creates a permeable, breathable film over the skin's surface. This barrier performs two main functions: it protects the skin from external irritants like allergens, pollutants, and friction, and it reduces transepidermal water loss (TEWL) by sealing in moisture [1.4.4, 1.6.2].
  • Acts as an Emollient: Dimethicone fills in the microscopic gaps between skin cells, which smooths the skin's surface and improves its softness and flexibility. This gives products containing it a characteristic silky, non-greasy "slip" [1.4.1, 1.4.3].
  • Improves Product Texture and Application: In cosmetic and skincare formulations, it enhances spreadability, allowing for a more uniform application of other ingredients, such as the physical filters in sunscreens [1.4.2]. It also gives products a lightweight, matte finish [1.4.4].
  • Aids in Scar Management: Silicone gels and sheets, which are primarily composed of dimethicone, have been shown to be effective in reducing the texture, color, and height of hypertrophic scars and keloids. The hydrating and protective environment it creates is believed to regulate collagen deposition during the healing process [1.4.2, 1.6.2].

Internal Use: Dimethicone as an Antiflatulent

Internally, dimethicone (as simethicone) works as a carminative and antifoaming agent to relieve symptoms of gas and bloating [1.3.2]. It does not prevent the formation of gas but works mechanically in the digestive tract. It lowers the surface tension of gas bubbles, causing them to coalesce into larger bubbles that are more easily passed from the body through belching or flatulence [1.3.2]. It is not absorbed into the bloodstream and is considered safe for internal use at recommended doses, even during pregnancy and breastfeeding [1.9.2].

Is Dimethicone Safe for Your Body?

For the vast majority of people, dimethicone is considered extremely safe for both topical and internal use [1.9.2]. Its large molecules prevent skin penetration, eliminating the risk of systemic toxicity from topical application [1.4.2]. Multiple safety assessments, including those by the CIR Expert Panel, have concluded it is non-toxic and not a carcinogen [1.4.1, 1.9.4].

One of the most common concerns is whether it clogs pores (comedogenicity). Scientific consensus and dermatological sources state that dimethicone is non-comedogenic, meaning it does not clog pores [1.10.1, 1.10.2, 1.10.3]. The breathable barrier it forms allows for the normal passage of substances like sweat and sebum [1.6.3]. However, some sources suggest its occlusive nature could potentially trap dirt and oil already on the skin if not cleansed properly, which might be a concern for acne-prone individuals [1.2.1].

Potential side effects are rare but can include [1.5.3, 1.5.1]:

  • Mild skin irritation, itching, or redness.
  • A feeling of dryness if it over-absorbs surface oils on very dry skin types [1.2.1].
  • Allergic reactions, though uncommon, can manifest as hives, swelling, or difficulty breathing and require immediate medical attention [1.5.1].

Dimethicone vs. Other Common Ingredients

A comparison helps to contextualize dimethicone's role in skincare.

Feature Dimethicone Petrolatum Hyaluronic Acid
Primary Function Skin protectant, emollient, occlusive [1.4.3, 1.6.4] Highly occlusive, skin protectant [1.8.4] Humectant (draws water into skin) [1.7.1, 1.7.2]
Texture & Feel Silky, smooth, non-greasy, matte finish [1.2.1, 1.8.1] Greasy, heavy feel [1.8.1] Can be tacky, but generally lightweight in formulations
Origin Synthetic (derived from silica) [1.4.1, 1.8.3] By-product of petroleum refining [1.8.3] Can be synthetic or derived from bio-fermentation [1.7.4]
Pore Clogging? No (non-comedogenic) [1.10.2] No (non-comedogenic) [1.8.2] No (non-comedogenic)
Mechanism Forms a breathable barrier to lock in moisture [1.6.2] Forms a strong barrier that is less breathable [1.8.2] Binds to water, hydrating the skin from within [1.7.2]

Environmental Considerations

While considered safe for human health, there are growing concerns about the environmental impact of silicones like dimethicone [1.11.3]. Because they are not readily biodegradable, they can accumulate in aquatic ecosystems after being washed down the drain [1.11.1, 1.11.4]. Scientists have found silicones in the blood of various animals, and some organizations express concern that they may be toxic to these ecosystems [1.11.1]. This environmental footprint is a key reason some consumers and brands are seeking silicone-free alternatives [1.11.2].

Conclusion

In summary, what dimethicone does to your body depends on its use. Topically, it is a safe and effective skin protectant and emollient that smooths skin, locks in moisture, and improves the texture of cosmetics without clogging pores. Internally, it is a safe and effective agent for relieving gas and bloating. While side effects and allergic reactions are rare, they can occur. The primary controversy surrounding dimethicone is not related to human health but to its environmental persistence.

Authoritative Link

Frequently Asked Questions

Yes, it is generally safe to use dimethicone on your face daily. It is non-comedogenic (won't clog pores) and its large molecular size prevents it from being absorbed into the skin, making it well-tolerated by most skin types [1.4.2, 1.10.2].

No, dimethicone is considered non-comedogenic and does not cause acne [1.10.1]. It forms a breathable barrier. However, if you don't cleanse your skin properly, it could theoretically trap oils or dirt already on the skin, so proper hygiene is important [1.2.1].

Simethicone is essentially 'activated' dimethicone. It is dimethicone mixed with silica gel, which enhances its antifoaming properties. Simethicone is the form typically used in oral medications for gas relief [1.3.2, 1.9.2].

No, dimethicone is not a microplastic or a plastic. It is a silicone, a polymer synthesized from the natural element silicon (found in silica and sand) [1.4.1, 1.8.3].

While uncommon, allergic reactions to dimethicone can occur. Symptoms may include redness, itching, swelling, or hives. If you experience these symptoms, stop using the product and consult a healthcare provider [1.5.3, 1.5.1].

There are environmental concerns associated with dimethicone and other silicones. They are not easily biodegradable and can accumulate in aquatic environments after being washed off. This has led some to seek silicone-free alternatives [1.11.1, 1.11.4].

Both are effective skin protectants, but dimethicone is derived from silica and feels lightweight and non-greasy, while petrolatum is from petroleum and feels heavier and greasier. Petrolatum is generally considered more occlusive than dimethicone [1.8.3, 1.8.1].

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.