Benzocaine is a topical anesthetic that works by temporarily blocking nerve signals in the area where it's applied, providing quick, localized pain relief. Because of its numbing properties, it is a popular active ingredient in a wide range of medications, from gels for toothaches to sprays for sore throats. However, the use of benzocaine is not without risk, and consumers should be aware of what products contain it and follow all safety instructions.
Oral and Dental Care Products
Benzocaine's numbing effect makes it highly effective for treating minor mouth pain. Many popular brands are available over the counter for temporary relief from issues like canker sores, gum irritation, and general mouth soreness.
Common Oral Brands:
- Orajel: One of the most widely recognized brands, available in various formulas for adult and infant oral pain relief. The FDA has warned against using benzocaine-containing products for teething in infants and children under 2 years of age.
- Anbesol: Similar to Orajel, Anbesol offers gels and liquids for instant oral pain relief. Maximum strength versions can contain up to 20% benzocaine.
- HurriCaine: Used by both healthcare professionals and consumers, this brand provides benzocaine in gel and spray forms for oral use.
- Kank-A: These products often include a unique applicator for targeted relief of canker sores and other mouth pain.
- Zilactin-B: A medicated gel designed for long-lasting relief of mouth sores.
Throat and Cough Relief Products
For soothing a sore throat, benzocaine is often combined with other ingredients like menthol for a cooling effect. These products are available as lozenges or sprays.
Common Throat Relief Brands:
- Cepacol: Offers lozenges and throat sprays for anesthetic and cough relief. The extra-strength formulations contain benzocaine for numbing sore throats.
- Chloraseptic: Available in sprays and lozenges, these products provide temporary relief from sore throat pain using benzocaine.
Topical and First-Aid Products
Benzocaine is also an ingredient in topical products used to relieve pain and itching from minor skin irritations.
Common Topical Brands:
- Lanacane: Known for its anti-itch and pain relief creams, which contain benzocaine.
- Dermoplast: This brand offers first-aid sprays with benzocaine to alleviate pain and itching from minor cuts, scrapes, and burns.
- Americaine: A topical anesthetic spray that also contains benzocaine.
- Solarcaine: A popular after-sun product, its sprays contain benzocaine to soothe sunburn pain. However, some sources advise against using benzocaine on sunburns, as it may cause irritation or allergic reactions in some individuals.
Specialized Products
Beyond common oral and topical applications, benzocaine is used in a few specialized products for specific needs.
- Ear Drops: Some otic products, such as Auralgan, combine benzocaine with other agents like antipyrine to relieve ear pain and help remove earwax.
- Hemorrhoid Ointments: Certain rectal ointments, like Americaine Hemorrhoidal Ointment, use benzocaine to numb the area and provide relief from hemorrhoidal pain and itching.
- Delay Sprays for Men: Some condoms and personal care sprays contain benzocaine to reduce penile sensitivity and help with premature ejaculation.
- Laxative Products: Certain enema products, like Enemeez Plus and Docusol Plus, contain benzocaine for localized numbing during administration.
Comparison Table: Common Benzocaine Products
| Product Category | Example Brand(s) | Typical Use(s) | Key Safety Information |
|---|---|---|---|
| Oral Gel | Orajel, Anbesol | Toothache, canker sores, gum pain | Do not use for teething in children under 2. Risk of methemoglobinemia. |
| Throat Lozenge | Cepacol, Chloraseptic | Sore throat pain, minor mouth irritation | Check age restrictions (typically not for under 5 years). Can be combined with menthol. |
| Topical Spray | Dermoplast, Solarcaine | Minor cuts, scrapes, burns, sunburns | Not recommended for large areas of damaged skin. Avoid eyes. Watch for allergic reactions. |
| Ear Drops | A/B Otic, Otocain | Ear pain, earwax removal | Used for otic conditions. Follow a doctor's instructions. |
| Rectal Ointment | Americaine, Benzocaine/Hydrocortisone combo | Hemorrhoid pain and itching | For external use only. Consult a doctor for prolonged use. |
Important Safety Considerations and FDA Warnings
The U.S. Food and Drug Administration (FDA) has issued specific warnings regarding benzocaine, primarily due to the risk of methemoglobinemia, a serious and sometimes fatal blood disorder.
- Use in Infants and Children: The FDA strongly recommends against using benzocaine-containing oral products for teething pain in infants and children under 2. This is because it offers little benefit and poses a significant risk of methemoglobinemia.
- Symptoms of Methemoglobinemia: Consumers and healthcare professionals should be aware of the signs of this condition, which can include pale, gray, or blue-colored skin, lips, and nail beds; shortness of breath; and fatigue.
- Use in Older Children and Adults: While less common, methemoglobinemia can also occur in older children and adults. Those with underlying health conditions such as asthma, heart disease, or certain genetic defects are at higher risk.
- Reading Labels: Always read the product label carefully to confirm the presence of benzocaine and to follow all usage instructions, especially age restrictions.
Conclusion
Benzocaine is a readily available and effective anesthetic for temporary pain relief. Found in numerous products for mouth sores, sore throats, and minor skin irritations, it provides localized numbing that can alleviate discomfort. However, the importance of using these products correctly cannot be overstated. With specific FDA warnings regarding the risks of methemoglobinemia, particularly in young children, it is essential to read labels, follow dosage recommendations, and be aware of the signs of adverse reactions. By understanding what drugs have benzocaine in them, consumers can use these products safely and effectively.
For more information on the FDA's warnings and guidelines concerning benzocaine products, consult their official communication on the matter: Risk of serious and potentially fatal blood disorder prompts FDA action on oral over-the-counter benzocaine products.
Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare professional before using any medication.
