Understanding Daily Cialis (Tadalafil)
Cialis, with the active ingredient tadalafil, is a prescription medication belonging to a class of drugs called PDE5 inhibitors [1.4.2]. It is primarily used to treat erectile dysfunction (ED) and the signs and symptoms of benign prostatic hyperplasia (BPH), an age-associated prostate gland enlargement [1.2.3, 1.7.3]. Unlike other ED medications that are taken as needed, Cialis is unique in that it can be prescribed in a low dose (typically 2.5mg or 5mg) to be taken every day [1.4.1, 1.4.6]. This daily regimen allows for a steady level of the medication in the body, enabling more spontaneous sexual activity without the need to plan a dose ahead of time [1.4.2]. For BPH, the 5mg daily dose helps alleviate lower urinary tract symptoms (LUTS) by relaxing muscles in the bladder and prostate [1.7.3, 1.7.4].
The Primary Effect of Stopping Daily Cialis: Return of Symptoms
The most immediate and significant consequence of discontinuing daily Cialis is the return of the symptoms it was managing. Cialis does not cure the underlying conditions of ED or BPH; it only manages their symptoms [1.2.1].
Return of Erectile Dysfunction
When you stop taking daily Cialis for ED, the medication's effect of relaxing blood vessels and increasing blood flow to the penis subsides [1.4.2]. As the drug clears from your system, you will likely revert to your baseline level of erectile function. Discontinuing Cialis does not cause physiological withdrawal symptoms [1.6.4]. However, some individuals may experience psychological dependence, where they rely on the medication for sexual confidence [1.2.4, 1.6.1].
Return of BPH Symptoms
For men taking daily Cialis for benign prostatic hyperplasia, stopping the medication will likely cause the return of lower urinary tract symptoms [1.7.1]. These can include increased urinary frequency, urgency, nighttime urination (nocturia), and a weak stream. The smooth muscle relaxation in the prostate and bladder, which tadalafil promotes, will cease, leading to the reappearance of these issues [1.7.4].
Pharmacokinetics: How Long Does Cialis Stay in Your System?
Tadalafil has a notably long half-life of approximately 17.5 hours [1.5.1, 1.5.3]. The half-life is the time it takes for half of the drug to be eliminated from the bloodstream. When taking Cialis daily, you achieve a steady-state concentration in about 5 days [1.5.2]. After you take your last dose, it takes roughly 3 to 4 days for the medication to be fully cleared from your system [1.2.3]. This can take longer in older adults or individuals with kidney or liver problems [1.2.3, 1.4.1]. Because any side effects are usually temporary, they will typically go away once the medication is stopped and has cleared the body [1.2.6].
Comparison: Daily Cialis vs. As-Needed Cialis
Choosing between a daily or as-needed regimen depends on lifestyle, frequency of sexual activity, and a doctor's recommendation [1.4.2].
| Feature | Daily Cialis (2.5mg, 5mg) | As-Needed Cialis (5mg, 10mg, 20mg) |
|---|---|---|
| Primary Use | Men who are sexually active two or more times per week; allows for spontaneity [1.4.2, 1.4.7]. Also for daily BPH treatment [1.4.5]. | Men who have sex less frequently and can plan ahead [1.4.7]. |
| Dosing | One pill taken at the same time each day [1.4.7]. | One pill taken at least 30 minutes before sexual activity [1.4.4]. |
| Onset of Action | Builds to a steady state in the body over about 5 days for full effect [1.4.6, 1.5.2]. | Works within 30 minutes to 2 hours after taking a dose [1.4.4]. |
| Duration of Effect | Provides a continuous level of medication in the body, so it is always 'active' [1.4.6]. | A single dose can be effective for up to 36 hours [1.5.1]. |
| Side Effects | Side effects may be milder due to the lower dose, but can be more persistent since the drug is always in the system [1.4.6]. | Side effects can be more noticeable due to the higher dose but are temporary as the drug leaves the system [1.4.2]. |
Is There a "Withdrawal"? Stopping Safely
There are no recognized physiological withdrawal symptoms associated with stopping Cialis [1.2.1, 1.6.4]. The medication is not physically addictive. It is considered safe to stop taking it at any time, but it is highly recommended to consult with your healthcare provider before doing so [1.2.2]. A doctor can discuss your reasons for stopping, whether it's due to side effects, cost, or a feeling that it's no longer needed. They can also explore alternative treatments or dosage adjustments if necessary [1.2.2]. For instance, if side effects are an issue, a lower dose might be an option. If effectiveness is a concern, a different medication could be considered [1.2.2].
Alternatives to Daily Cialis
If daily Cialis is not the right fit, or if you are looking for other options after stopping, several alternatives are available for both ED and BPH.
For Erectile Dysfunction:
- Other PDE5 Inhibitors: Sildenafil (Viagra), Vardenafil (Levitra, Staxyn), and Avanafil (Stendra) are other oral medications that work similarly but have different durations of action and side effect profiles [1.8.1].
- Injections and Pellets: Alprostadil can be administered as a penile injection (Caverject) or a urethral pellet (Muse) [1.8.1, 1.8.6].
- Lifestyle Changes: Improvements in diet, increased exercise, weight loss, and smoking cessation can have a significant positive impact on erectile function [1.8.1].
For BPH:
- Alpha-blockers: Medications like tamsulosin relax bladder and prostate muscles to improve urine flow.
- 5-alpha reductase inhibitors: Drugs like finasteride can shrink the prostate over time.
It is essential to discuss these alternatives with a healthcare provider to find the most suitable and safe option for your specific health needs [1.8.1].
Conclusion
Stopping daily Cialis is a straightforward process that does not cause physical withdrawal. However, the primary outcome is the likely return of the original ED or BPH symptoms that the medication was managing [1.2.1]. The drug takes several days to completely leave the system, after which you will return to your baseline condition [1.2.3]. Always consult a doctor before discontinuing any prescription medication to discuss the reasons and explore alternative pathways for managing your health effectively and safely [1.2.2].
For more information on Tadalafil, you can visit the National Library of Medicine's page on the drug.
