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What is a 404 pill? Understanding Amphetamine/Dextroamphetamine and Other Medications

3 min read

According to Drugs.com, a round, orange pill with the imprint 'E 404' has been identified as a 30 mg dosage of amphetamine and dextroamphetamine, a Schedule II controlled substance. Understanding precisely what a 404 pill is requires confirming all identifying markings, including the full imprint, shape, and color, as this number can appear on multiple different medications.

Quick Summary

The term '404 pill' does not refer to a single medication but can indicate several different drugs depending on the imprint code. The most commonly referenced is the orange E 404, a stimulant for ADHD and narcolepsy, but others exist for unrelated conditions. Proper identification is crucial for safety.

Key Points

  • Identity Confusion: The term '404 pill' is an incomplete and misleading identifier, as different medications from various manufacturers use '404' within their imprint codes.

  • E 404 is a Stimulant: The most common reference, the orange, round E 404, is a generic version of Adderall containing amphetamine/dextroamphetamine, used for ADHD and narcolepsy.

  • High Potential for Abuse: As a Schedule II controlled substance, E 404 carries a high risk of dependence and addiction, and should only be used as prescribed by a doctor.

  • Other '404' Pills Exist: Pills with a '404' imprint can be completely different, such as the antihistamine ADG 404 (white) or the UTI antibiotic Lifestar 404 (brown/gray).

  • Verify with a Professional: Due to the variety of medications and potential risks, it is essential to verify any pill with a complete imprint and consult a doctor or pharmacist for accurate identification.

  • Serious Side Effects: The E 404 stimulant can cause severe cardiovascular and psychiatric side effects, and dangerous interactions with other substances like MAOIs or alcohol.

  • Never Self-Medicate: Misuse or unprescribed use of any medication, especially a controlled substance like E 404, can lead to fatal overdose.

In This Article

What does '404 pill' signify?

Searching for information on a '404 pill' can lead to confusion because multiple medications use this number as part of their unique imprint code. The specific imprint, color, and shape are necessary to properly identify any pill. The most prevalent result for a '404 pill' refers to the orange, round 'E 404' tablet, a generic form of Adderall. However, other pills, such as the white ADG 404 and the brown/gray Lifestar 404, have very different active ingredients and uses. Misidentifying a medication can have serious health consequences, so proper verification by a medical professional or pharmacist is always recommended.

The most common '404' pill: E 404 (Amphetamine/Dextroamphetamine)

The orange, round tablet marked with 'E 404' contains a combination of amphetamine and dextroamphetamine, and it is a central nervous system (CNS) stimulant. This medication is most commonly prescribed for the treatment of attention-deficit hyperactivity disorder (ADHD) and narcolepsy. The two active ingredients work by increasing the levels of certain neurotransmitters in the brain, such as norepinephrine and dopamine, which helps improve focus, reduce hyperactivity, and enhance alertness.

Therapeutic uses of E 404

  • ADHD: By influencing neurotransmitter levels, E 404 helps manage the core symptoms of ADHD, such as inattention, impulsivity, and hyperactivity. As part of a comprehensive treatment plan, it can improve a person's ability to focus and control their behavior.
  • Narcolepsy: For individuals with narcolepsy, a sleep disorder causing excessive daytime sleepiness, this medication promotes wakefulness and alertness.

Side effects and risks of E 404

Like all CNS stimulants, E 404 is associated with potential side effects, which range from mild to severe.

Common side effects

  • Insomnia
  • Loss of appetite and weight loss
  • Dry mouth
  • Headache
  • Nervousness or anxiety
  • Increased heart rate

Serious risks and side effects

  • Cardiovascular issues: This medication can increase heart rate and blood pressure, potentially leading to serious complications like heart attack, stroke, or sudden death, especially in individuals with pre-existing heart conditions.
  • Psychiatric problems: Amphetamine/dextroamphetamine can cause or worsen mental health issues, including psychosis, aggression, hallucinations, or mania.
  • Dependence and abuse: Classified as a Schedule II controlled substance, E 404 has a high potential for misuse, dependence, and addiction. Overdose is a significant risk, particularly with unapproved methods of administration.
  • Serotonin syndrome: This is a life-threatening condition that can occur when amphetamines are combined with other drugs that affect serotonin levels, such as MAOIs or certain antidepressants.

E 404: A generic form of Adderall

For clarification, the E 404 orange pill is a generic version of the brand-name medication Adderall. Both contain the same active ingredients, amphetamine and dextroamphetamine, and produce similar therapeutic effects. They are also subject to the same strict controls due to their abuse potential.

Other medications identified by '404' imprints

To highlight the importance of careful identification, here are two other examples of pills that feature '404' as part of their markings:

  • ADG 404: A white, round pill with the imprint 'ADG 404' is Carbinoxamine Maleate, an antihistamine used to treat various allergy symptoms, including allergic rhinitis. This medication is not a controlled substance and belongs to a completely different drug class than E 404.
  • Lifestar 404: A brown and gray capsule marked 'Lifestar 404' is Nitrofurantoin, a urinary anti-infective prescribed to treat urinary tract infections (UTIs). It is also not a controlled substance.

Comparison of different '404' pills

Feature E 404 (Orange, Round) ADG 404 (White, Round) Lifestar 404 (Brown/Gray, Capsule)
Active Ingredient Amphetamine / Dextroamphetamine Carbinoxamine Maleate Nitrofurantoin (Monohydrate/Macrocrystals)
Drug Class CNS Stimulant Antihistamine Urinary Anti-infective
Primary Use ADHD, Narcolepsy Allergic Rhinitis, Allergies Urinary Tract Infections (UTIs)
Controlled Substance? Yes (Schedule II) No No
Manufacturer Sandoz Pharmaceuticals Inc. Mikart, Inc. Lifestar Pharma LLC

Conclusion

While the term '404 pill' most frequently refers to the orange E 404, a generic version of Adderall for ADHD and narcolepsy, it is crucial to recognize that this is not the only medication identified by this number. Other pills, like the antihistamine ADG 404 and the antibiotic Lifestar 404, also feature '404' in their imprints. Attempting to identify a pill based on a partial imprint alone is dangerous and can lead to accidental misuse or serious health complications. Always confirm the full imprint code, shape, and color, and consult with a healthcare provider or pharmacist for accurate medication identification. Following a doctor's instructions for any prescription medication is the safest approach to treatment.

For more detailed information on prescription medications and pill identification, resources like Drugs.com can be highly beneficial when used in conjunction with professional medical advice.

Frequently Asked Questions

The orange E 404 pill, a stimulant, has common side effects including insomnia, loss of appetite, dry mouth, headache, nervousness, and an increased heart rate. Any persistent or severe side effects should be discussed with a doctor.

Combining the E 404 pill with certain other medications can be dangerous. It should not be taken with MAO inhibitors or other stimulants. Always disclose all medications, including over-the-counter and herbal supplements, to your doctor before taking E 404.

To distinguish between different '404' pills, you must look at the full imprint, shape, and color. For example, the stimulant E 404 is orange and round, while the antihistamine ADG 404 is white and round, and the antibiotic Lifestar 404 is a brown/gray capsule.

The E 404 pill contains amphetamine/dextroamphetamine and is a Schedule II controlled substance with a high potential for abuse, dependence, and addiction. Misuse can lead to serious health problems, overdose, and even death.

Yes, alternatives to stimulant medications like E 404 exist. Non-stimulant options such as atomoxetine (Strattera), guanfacine (Intuniv), and clonidine (Kapvay) are available and may be suitable for those with ADHD.

If you find an unidentified pill, do not take it. Use a pill identifier tool online, being careful to match the full imprint, shape, and color. The safest course of action is to bring it to a pharmacist for positive identification.

Overdose symptoms for the E 404 stimulant include severe confusion, agitation, rapid heartbeat, high fever, hallucinations, and seizures. If you suspect an overdose, call emergency services immediately.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.